Having the same problem. Game loads up fine, was actually running great prior to I21, now it runs then maps out. Here's my Hijack this.
Logfile of Trend Micro HijackThis v2.0.4
Scan saved at 7:39:15 AM, on 10/23/2011
Platform: Windows XP SP3 (WinNT 5.01.2600)
MSIE: Internet Explorer v8.00 (8.00.6001.18702)
Boot mode: Normal
Running processes:
F:\WINDOWS\System32\smss.exe
F:\WINDOWS\system32\winlogon.exe
F:\WINDOWS\system32\services.exe
F:\WINDOWS\system32\lsass.exe
F:\WINDOWS\system32\svchost.exe
F:\WINDOWS\System32\svchost.exe
F:\WINDOWS\system32\svchost.exe
F:\WINDOWS\system32\spoolsv.exe
F:\Program Files\Avira\AntiVir Desktop\sched.exe
F:\Program Files\Belkin\Router Setup and Monitor\BelkinService.exe
F:\Program Files\Avira\AntiVir Desktop\avguard.exe
F:\Program Files\Application Updater\ApplicationUpdater.exe
F:\Program Files\Bonjour\mDNSResponder.exe
F:\Program Files\Motorola Media Link\NServiceEntry.exe
F:\WINDOWS\system32\gearsec.exe
F:\WINDOWS\System32\svchost.exe
F:\PROGRA~1\Iomega\System32\AppServices.exe
F:\Program Files\Java\jre7\bin\jqs.exe
F:\Program Files\Common Files\LightScribe\LSSrvc.exe
F:\Program Files\Common Files\Mcafee\McSvcHost\McSvHost.exe
F:\WINDOWS\system32\mfevtps.exe
F:\Program Files\Nero\Nero8\Nero BackItUp\NBService.exe
F:\WINDOWS\system32\nvsvc32.exe
F:\WINDOWS\system32\HPZipm12.exe
F:\WINDOWS\system32\svchost.exe
F:\Program Files\UPHClean\uphclean.exe
F:\Program Files\Western Digital\WD SmartWare\WDRulesEngine.exe
F:\Program Files\Avira\AntiVir Desktop\avshadow.exe
F:\WINDOWS\system32\MsPMSPSv.exe
F:\WINDOWS\system32\SearchIndexer.exe
F:\Program Files\Common Files\McAfee\SystemCore\mcshield.exe
F:\Program Files\Common Files\McAfee\SystemCore\mfefire.exe
F:\Program Files\Western Digital\WD SmartWare\WDFME.exe
F:\WINDOWS\Explorer.EXE
F:\WINDOWS\system32\rundll32.exe
F:\WINDOWS\stsystra.exe
F:\Program Files\Logitech\SetPointP\SetPoint.exe
F:\WINDOWS\ehome\ehtray.exe
F:\Program Files\Belkin\Router Setup and Monitor\BelkinRouterMonitor.exe
F:\WINDOWS\system32\RunDLL32.exe
F:\Program Files\Common Files\Spigot\Search Settings\SearchSettings.exe
F:\Program Files\Avira\AntiVir Desktop\avgnt.exe
F:\Program Files\Windows Media Player\WMPNSCFG.exe
F:\Program Files\Common Files\LogiShrd\KHAL3\KHALMNPR.EXE
F:\Program Files\McAfee.com\Agent\mcagent.exe
F:\Program Files\City of Heroes\CityOfHeroes.exe
f:\Program Files\Zune\ZuneBusEnum.exe
F:\Program Files\Motorola\MotoHelper\MotoHelperAgent.exe
F:\Program Files\Motorola\MotoHelper\MotoHelperService.exe
F:\Program Files\Mozilla Firefox\firefox.exe
F:\Program Files\Mozilla Firefox\plugin-container.exe
F:\WINDOWS\system32\SearchProtocolHost.exe
F:\WINDOWS\system32\msiexec.exe
F:\Program Files\HijackThis\Trend Micro\HiJackThis\HiJackThis.exe
R0 - HKCU\Software\Microsoft\Internet Explorer\Main,Start Page =
R1 - HKLM\Software\Microsoft\Internet Explorer\Main,Default_Page_URL =
http://go.microsoft.com/fwlink/?LinkId=69157
R1 - HKLM\Software\Microsoft\Internet Explorer\Main,Default_Search_URL =
http://go.microsoft.com/fwlink/?LinkId=54896
R1 - HKLM\Software\Microsoft\Internet Explorer\Main,Search Page =
http://go.microsoft.com/fwlink/?LinkId=54896
R0 - HKLM\Software\Microsoft\Internet Explorer\Main,Start Page =
http://go.microsoft.com/fwlink/?LinkId=69157
R0 - HKCU\Software\Microsoft\Internet Explorer\Main,Local Page =
R1 - HKCU\Software\Microsoft\Windows\CurrentVersion\Int ernet Settings,ProxyOverride = 192.168.*.*;*.local
R3 - URLSearchHook: YouTube Downloader Toolbar - {F3FEE66E-E034-436a-86E4-9690573BEE8A} - (no file)
R3 - URLSearchHook: (no name) - {81017EA9-9AA8-4A6A-9734-7AF40E7D593F} - (no file)
O2 - BHO: (no name) - {02478D38-C3F9-4efb-9B51-7695ECA05670} - (no file)
O2 - BHO: AcroIEHelperStub - {18DF081C-E8AD-4283-A596-FA578C2EBDC3} - F:\Program Files\Common Files\Adobe\Acrobat\ActiveX\AcroIEHelperShim.dll
O2 - BHO: scriptproxy - {7DB2D5A0-7241-4E79-B68D-6309F01C5231} - F:\Program Files\Common Files\McAfee\SystemCore\ScriptSn.20111022093147.dl l
O2 - BHO: McAfee SiteAdvisor BHO - {B164E929-A1B6-4A06-B104-2CD0E90A88FF} - f:\PROGRA~1\mcafee\SITEAD~1\mcieplg.dll
O2 - BHO: Java(tm) Plug-In 2 SSV Helper - {DBC80044-A445-435b-BC74-9C25C1C588A9} - F:\Program Files\Java\jre7\bin\jp2ssv.dll
O2 - BHO: YouTube Downloader Toolbar - {F3FEE66E-E034-436a-86E4-9690573BEE8A} - (no file)
O3 - Toolbar: (no name) - {9D425283-D487-4337-BAB6-AB8354A81457} - (no file)
O3 - Toolbar: YouTube Downloader Toolbar - {F3FEE66E-E034-436a-86E4-9690573BEE8A} - (no file)
O3 - Toolbar: McAfee SiteAdvisor Toolbar - {0EBBBE48-BAD4-4B4C-8E5A-516ABECAE064} - f:\PROGRA~1\mcafee\SITEAD~1\mcieplg.dll
O4 - HKLM\..\Run: [SigmatelSysTrayApp] stsystra.exe
O4 - HKLM\..\Run: [igfxtray] F:\WINDOWS\system32\igfxtray.exe
O4 - HKLM\..\Run: [igfxhkcmd] F:\WINDOWS\system32\hkcmd.exe
O4 - HKLM\..\Run: [igfxpers] F:\WINDOWS\system32\igfxpers.exe
O4 - HKLM\..\Run: [Adobe ARM] "F:\Program Files\Common Files\Adobe\ARM\1.0\AdobeARM.exe"
O4 - HKLM\..\Run: [EvtMgr6] F:\Program Files\Logitech\SetPointP\SetPoint.exe /launchGaming
O4 - HKLM\..\Run: [ehTray] F:\WINDOWS\ehome\ehtray.exe
O4 - HKLM\..\Run: [InstaLAN] "F:\Program Files\Belkin\Router Setup and Monitor\BelkinRouterMonitor.exe" startup
O4 - HKLM\..\Run: [LWS] F:\Program Files\Logitech\LWS\Webcam Software\LWS.exe -hide
O4 - HKLM\..\Run: [NvCplDaemon] RUNDLL32.EXE F:\WINDOWS\system32\NvCpl.dll,NvStartup
O4 - HKLM\..\Run: [NvMediaCenter] RunDLL32.exe NvMCTray.dll,NvTaskbarInit -login
O4 - HKLM\..\Run: [nwiz] F:\Program Files\NVIDIA Corporation\nView\nwiz.exe /installquiet
O4 - HKLM\..\Run: [SearchSettings] "F:\Program Files\Common Files\Spigot\Search Settings\SearchSettings.exe"
O4 - HKLM\..\Run: [avgnt] "F:\Program Files\Avira\AntiVir Desktop\avgnt.exe" /min
O4 - HKLM\..\Run: [mcui_exe] "F:\Program Files\McAfee.com\Agent\mcagent.exe" /runkey
O4 - HKCU\..\Run: [WMPNSCFG] F:\Program Files\Windows Media Player\WMPNSCFG.exe
O9 - Extra button: Blog This - {219C3416-8CB2-491a-A3C7-D9FCDDC9D600} - F:\Program Files\Windows Live\Writer\WriterBrowserExtension.dll
O9 - Extra 'Tools' menuitem: &Blog This in Windows Live Writer - {219C3416-8CB2-491a-A3C7-D9FCDDC9D600} - F:\Program Files\Windows Live\Writer\WriterBrowserExtension.dll
O9 - Extra button: (no name) - {e2e2dd38-d088-4134-82b7-f2ba38496583} - F:\WINDOWS\Network Diagnostic\xpnetdiag.exe
O9 - Extra 'Tools' menuitem: @xpsp3res.dll,-20001 - {e2e2dd38-d088-4134-82b7-f2ba38496583} - F:\WINDOWS\Network Diagnostic\xpnetdiag.exe
O9 - Extra button: Messenger - {FB5F1910-F110-11d2-BB9E-00C04F795683} - F:\Program Files\Messenger\msmsgs.exe
O9 - Extra 'Tools' menuitem: Windows Messenger - {FB5F1910-F110-11d2-BB9E-00C04F795683} - F:\Program Files\Messenger\msmsgs.exe
O15 - Trusted IP range:
http://192.168.2.1
O15 - ESC Trusted IP range:
http://192.168.2.1
O16 - DPF: {5AE58FCF-6F6A-49B2-B064-02492C66E3F4} (MUCatalogWebControl Class) -
http://catalog.update.microsoft.com/...?1301156195890
O16 - DPF: {6414512B-B978-451D-A0D8-FCFDF33E833C} (WUWebControl Class) -
http://update.microsoft.com/windowsu...?1262464802734
O16 - DPF: {6E32070A-766D-4EE6-879C-DC1FA91D2FC3} (MUWebControl Class) -
http://www.update.microsoft.com/micr...?1260407755359
O16 - DPF: {E2883E8F-472F-4FB0-9522-AC9BF37916A7} -
http://platformdl.adobe.com/NOS/getPlusPlus/1.6/gp.cab
O18 - Protocol: dssrequest - {5513F07E-936B-4E52-9B00-067394E91CC5} - f:\PROGRA~1\mcafee\SITEAD~1\mcieplg.dll
O18 - Protocol: sacore - {5513F07E-936B-4E52-9B00-067394E91CC5} - f:\PROGRA~1\mcafee\SITEAD~1\mcieplg.dll
O22 - SharedTaskScheduler: Browseui preloader - {438755C2-A8BA-11D1-B96B-00A0C90312E1} - F:\WINDOWS\system32\browseui.dll
O22 - SharedTaskScheduler: Component Categories cache daemon - {8C7461EF-2B13-11d2-BE35-3078302C2030} - F:\WINDOWS\system32\browseui.dll
O23 - Service: AffinegyService - Affinegy, Inc. - F:\Program Files\Belkin\Router Setup and Monitor\BelkinService.exe
O23 - Service: Avira Scheduler (AntiVirSchedulerService) - Avira Operations GmbH & Co. KG - F:\Program Files\Avira\AntiVir Desktop\sched.exe
O23 - Service: Avira Realtime Protection (AntiVirService) - Avira Operations GmbH & Co. KG - F:\Program Files\Avira\AntiVir Desktop\avguard.exe
O23 - Service: Application Updater - Spigot, Inc. - F:\Program Files\Application Updater\ApplicationUpdater.exe
O23 - Service: Bonjour Service - Apple Inc. - F:\Program Files\Bonjour\mDNSResponder.exe
O23 - Service: DeviceMonitorService - Nero AG - F:\Program Files\Motorola Media Link\NServiceEntry.exe
O23 - Service: GearSecurity - GEAR Software - F:\WINDOWS\system32\gearsec.exe
O23 - Service: Iomega App Services - Iomega Corporation - F:\PROGRA~1\Iomega\System32\AppServices.exe
O23 - Service: iPod Service - Apple Inc. - F:\Program Files\iPod\bin\iPodService.exe
O23 - Service: Java Quick Starter (JavaQuickStarterService) - Oracle Corporation - F:\Program Files\Java\jre7\bin\jqs.exe
O23 - Service: Logitech Bluetooth Service (LBTServ) - Logitech, Inc. - F:\Program Files\Common Files\LogiShrd\Bluetooth\lbtserv.exe
O23 - Service: LightScribeService Direct Disc Labeling Service (LightScribeService) - Hewlett-Packard Company - F:\Program Files\Common Files\LightScribe\LSSrvc.exe
O23 - Service: McAfee SiteAdvisor Service - McAfee, Inc. - F:\Program Files\Common Files\Mcafee\McSvcHost\McSvHost.exe
O23 - Service: McAfee Personal Firewall Service (McMPFSvc) - McAfee, Inc. - F:\Program Files\Common Files\Mcafee\McSvcHost\McSvHost.exe
O23 - Service: McAfee Services (mcmscsvc) - McAfee, Inc. - F:\Program Files\Common Files\Mcafee\McSvcHost\McSvHost.exe
O23 - Service: McAfee VirusScan Announcer (McNaiAnn) - McAfee, Inc. - F:\Program Files\Common Files\Mcafee\McSvcHost\McSvHost.exe
O23 - Service: McAfee Network Agent (McNASvc) - McAfee, Inc. - F:\Program Files\Common Files\Mcafee\McSvcHost\McSvHost.exe
O23 - Service: McAfee Scanner (McODS) - McAfee, Inc. - F:\Program Files\McAfee\VirusScan\mcods.exe
O23 - Service: McAfee Proxy Service (McProxy) - McAfee, Inc. - F:\Program Files\Common Files\Mcafee\McSvcHost\McSvHost.exe
O23 - Service: McShield - McAfee, Inc. - F:\Program Files\Common Files\McAfee\SystemCore\\mcshield.exe
O23 - Service: MemeoBackgroundService - Memeo - F:\Program Files\Memeo\AutoBackup\MemeoBackgroundService.exe
O23 - Service: McAfee Firewall Core Service (mfefire) - McAfee, Inc. - F:\Program Files\Common Files\McAfee\SystemCore\\mfefire.exe
O23 - Service: McAfee Validation Trust Protection Service (mfevtp) - McAfee, Inc. - F:\WINDOWS\system32\mfevtps.exe
O23 - Service: MotoHelper Service (MotoHelper) - Unknown owner - F:\Program Files\Motorola\MotoHelper\MotoHelperService.exe
O23 - Service: Nero BackItUp Scheduler 3 - Nero AG - F:\Program Files\Nero\Nero8\Nero BackItUp\NBService.exe
O23 - Service: NMIndexingService - Nero AG - F:\Program Files\Common Files\Nero\Lib\NMIndexingService.exe
O23 - Service: NVIDIA Driver Helper Service (NVSvc) - NVIDIA Corporation - F:\WINDOWS\system32\nvsvc32.exe
O23 - Service: NVIDIA Update Service Daemon (nvUpdatusService) - NVIDIA Corporation - F:\Program Files\NVIDIA Corporation\NVIDIA Updatus\daemonu.exe
O23 - Service: Pml Driver HPZ12 - HP - F:\WINDOWS\system32\HPZipm12.exe
O23 - Service: Seagate Dashboard Service (SeagateDashboardService) - Memeo - F:\Program Files\Seagate\Seagate Dashboard\SeagateDashboardService.exe
O23 - Service: Steam Client Service - Valve Corporation - F:\Program Files\Common Files\Steam\SteamService.exe
O23 - Service: WDDMService - WDC - F:\Program Files\Western Digital\WD SmartWare\WDDMService.exe
O23 - Service: WDFMEService - Western Digital - F:\Program Files\Western Digital\WD SmartWare\WDFME.exe
O23 - Service: WDRulesService - Western Digital - F:\Program Files\Western Digital\WD SmartWare\WDRulesEngine.exe
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End of file - 11879 bytes