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Not only that but in the Doctors Wife the Doctor states that the Corsair regenerated into a female and back again a few times. So it can happen
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Originally Posted by Tormentoso
First thing the current regeneration did was touch his hear and scream "I'm a girl!" before going to his adam's apple and confirming otherwise. Maybe it was a thrown in joke, but at least there's precedent it can happen.
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(After all, I'm fairly cool toward Tom Baker most of the time, but like the fifth and sixth doctors... and people are really down on Colin Baker.) 


