DB Combo Opinions

Which do you think are more worth pursuing for a scrapper?

The best one is Attack Vitals, then Sweep. I don't like to go for Sweep because I don't like One Thousand Cuts but other people do like it a lot.

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I don't like to go for Sweep because I want to get away with as few attacks as possible (though I'd consider a Blinding Feint -> Sweep build). But yeah, Attack Vitals, then Sweep, then probably don't bother unless it's just for fun. The top chains don't use the combos at all, but they require hyper-recharge builds to pull off. The classic high-end chain at rather moderate recharge is Blinding Feint -> Attack Vitals.

You need +128% recharge in Blinding Feint for the standard Blinding Feint -> Attack Vitals chain. That's the standard DPS chain, and by far the most practical. If you can't swing +128%, it's reasonable to add a Power Slice at the end, which cuts the recharge requirement down to +75% in Blinding Feint, which should be trivial in an end game build.

For Blinding Feint -> Ablating Strike -> Sweeping Strike -> Ablating Strike, I'd probably want about +280% recharge in Ablating Strike or higher. You'll still be running with a gap, but it's a tiny gap, and the DPS is huge with the right slotting (purples, Achilles' Heel and Gladiator).

Also worth considering is Blinding Feint -> Ablating Strike -> Sweeping Strike. The DPS is about mid way between the two previous chains, but the cone AoE damage is somewhat higher, so it's a good alternative for general play instead of AV killing. Again, I'd probably want +280% recharge and up for it. It's going to run with a larger gap too. On the other hand, that means it benefits more from Speed Boosts and the like.

Unless I was specifically going for a DPS build, I'd just stick with the standard Blinding Feint -> Attack Vitals for my single-target damage. The recharge for the other chains would completely dominate the build, and cost an arm and a leg as well.

The standard DPS chain uses Vengeful Slice, of course, so it sounds like it isn't something you want. Other than the standard and the top two chains, I haven't studied Dual Blades chains much, so I don't really have something to suggest for the attacks you do want to take.

Personally I don't think Sweep combo is worth it, you would get more milage out of the Flame mastery pool and Empower is nice

My combo consists of Empower Combo --> Typhoon's Edge --> Fireball --> Empower Combo --> Attack Vitals,

the extra 50% damage from empower gives Typhoons edge an extra 35 points of damage, it gives the Attack Vitals combo a total extra of about 80 points of damage and adds about 28 points of damage to fireball

So Yes AV, possibly sweep, maybe empower, no weaken, but don't worry about any of it too much, at least until endgame?

The others already covered most aspects. Lets take another look on the DB combos to get some deeper insight.

There are four attack combinations:
Empower: Nimble Slash -> Ablating Strike -> Blinding Feint.
Weaken: Nimble Slash -> Ablating Strike -> Typhoon's Edge
Attack Vitals: Ablating Strike -> Vengeful Slice -> Sweeping Strike
Sweep: One Thousand Cuts -> Power Slice -> Typhoon's Edge

If you execute the respective attack chain successfully you will get a special bonus from that combination that is added to the last attack in the chain.

Empower: Blinding Feint gives +10% ToHit and +37.5% DMG buff for 10s. With Empower BF gives +13.3% ToHit and +50% DMG buff for 10s (the ToHit part is enhanceable). Damage is not affected (except for the DMG buff, of course). This is the weakest combo. The extra +12.5% DMG buff isn't enough to compensate for the low damage output from the Empower attack chain. Even worse is the large gap between Empower and Attack Vitals, your ST damage attack chain. It appears because AS needs much longer to recharge (6s) than BF needs to execute (1.2s). This will eat up some of your buffed time (~15-30% est. after conventional slotting) and lowers your DPS. Using Empower to buff AoE is bad as well. All the attacks in the Empower chain are ST and they're not even very strong, hurting your AoE efficiency very much. It is MUCH better to only use BF in conjunction with either Attack Vitals or Sweep. Both attack chains are short enough (after slotting) to have the BF buff up continuously and they're good against ST (Attack Vitals) and AoE (Sweep).

Weaken: Typhoon's Edge with Weaken will provide -7.5% ToHitDebuff and -7.5% DefenseDebuff for 20s on a successful hit. Damage is not affected. Weaken is better than Empower but not much. It's a bit weak on the damage side and is not very end efficient when you fight single targets or small spawns. The debuff is always nice but not really needed in the higher levels.

Attack Vitals: Sweeping Strike with Attack Vitals will add 5*12.51 lethal DoT (enhanceable) over 4.1s (basic damage is 106.36). Not only a good combo but actually the best attack chain on an affordable build when paired with Blinding Feint (the best attack chain is probably BF – AS – SS – AS slotted to the max including both -Res procs, but it is difficult and expensive to get the +recharge needed, especially on secondary powersets other than SR and Elec – c.w. Werner's posts above).

Sweep: Typhoon's Edge with Sweep will add 35.66 lethal damage (enhanceable) and +0.67 Knockdown (basic damage is 2*35.66). The KD adds to your survivability (some targets are immune to KD, though) and the AoE damage is quite good (needs a little practice to aim your cones right). BF -> Sweep and BF -> SS -> Sweep are your best AoE attack chains (SS with the -Res proc). The tug on endurance is noticeable, though.