One of the "natural" natural combos is a Martial Arts/Willpower scrapper - minimal "super" fx, an OK single-target primary and good secondary that gives you the option of skipping the Fitness pool.
Maybe Super Reflexes as the secondary, although there you'll probably have to bring Fitness back into the picture.
Edit: Removed now-redundant P.S. 
You need to wait for super strength to come to scrappers, then you can slap them about like big daddy.
or as said above, MA/SR or MA/WP afteral, you can't say that Bond doesn't have will power (unless it comes to ladies....)
Or you could always just make a Thugs MM 
The following information is classified. You must have security level 7 to proceed. Please enter password now.
Password: Jimjamjaroo
Code Name: Agent Blade
Birthplace: The outskirts of talos island.
Specialty: Has mastered the arts of the katana to deadly effect, finishing his enemies both swiftly and effeciently with minimal ease. His willpower is second to none in the elite group, while many of the group will fall, agent blade will get back up and continue to fight.
Well its a possibility 
@Damz Find me on the global channel Union Chat. One of the best "chat channels" ingame!
ok so issue 13 will be live any min, and i dont know if youve seen the new cossys we get, but i have and you get a whole new selection of suits! ones that actualy look like suits this time! ive always wanted to make a agent toon but never had the right cossy for it, but with the new cossys im inspired! so i know how im gunna dress my agent i know his back story, so what powers can i give him? im thinking of keeping him natural which in the past ive thought of blaster guns/devices but that seems awfully boring! so if you could come up with some good power sets that would match an agent toon we can always scrap the idea that he only has to be natural but i dont want to make him too super. any ideas?