Repel 1-3 end reductions
Fulcrum shift 2 Accuracy, 3 recharge
Transference 2 accuracy, and a mix of end mods and recharge
Inertial reduction works fine with one slot, recharge or jump height depending on preference
Speed boost 1-3 end mods
Increase density 1-3 resistance
Siphon speed 2 accuracy, 3 recharge, and a slow modifier if you want to be fasterer
Siphon power, 2 acc, 2-3 recharge
Transfusion 2-3 acc, rest a mix of heal and recharge.
Recommend swift rather than Health.
All attacks slotted 1-2 acc, 3 damage.
DON'T eat muffins while I'm developing you.
Pants! Turkey Magnates! A man in a box! Rogue AI! Come one, come all, to arc ID 10107 - It's [i]'Not as long as some other arcs'[/i]!
What he said, pretty much. 
Defiant 50's
Many and varied!
@Miss Chief
Personally I found health with its slight sleep resitance more useful then swift for my kin. But your mileage may vary.
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What he said, pretty much.
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QFT 
thePhilosopher Martial Arts/Regen/Fire Scrapper
theRegulator Empathy/Energy/Soul Defender
Total Inertia Ice Blast/Kinetics/Psy Corruptor
Total Inferno Ice Blast/Thermal/Leviathan Corruptor
get as many acc enhances in stuff as you can, better to hit more & do some than miss & do nothing. I found that Transference seems to have a lousy accuracy, may just be me & I have 3 in Fulcrum Shift, cos ...well you don't wanna mis now do you?
With a couple of recharges in Transfusion, siphon speed & hasten on the go, you will be healing those greatful melee people about every 6 seconds or there abouts, is lush.
The Good:
Krazy Mary L50 Kinetic defender
Uniqua L31 PeaceBringer
Black Annis L24 Warshade
Krystal L18 Ice Blaster
The Bad:
Frenzi L34 SS/Inv Brute
just notioced you don't have any leadership powers. With 3 slotted tactics it acts like 1 extra SO in everything, so IMO it's worth trying to fit in somewhere.
Defiant 50's
Many and varied!
@Miss Chief
Especially if the precursor to it (Assault) is being wangled in anyway!
DON'T eat muffins while I'm developing you.
Pants! Turkey Magnates! A man in a box! Rogue AI! Come one, come all, to arc ID 10107 - It's [i]'Not as long as some other arcs'[/i]!
What role you planning on playing? PvP build or non PvP buils? Pure Support or offender? Or just a hybrid??
I'll hit ya back with some advice, and post my build when i get home
PvE Offender
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PvE Offender
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Drop the Snipe, you don't have a way of getting it safely off when combat is started. As a PvE Offender you'll want a decent single target cycle, Sniper attacks only help with this if you have Defense, ToHit Debuffs or someone else taking ALL the aggro.
Get Power Blast instead of Torrent at 4.
Get Torrent instead of ID at 8.
Get ID at 16 (instead of the Snipe).
Tactics will help you more than Explosive Blast. It'll let you slot less Accuracy in all of your powers, making it possible to slot for other effects.
Explosive blast is only any good for the whooo big bang effect. If you want to get in take advantage of your fulcrum shift, then I went the acrobatics route, I know that inertial red does SJ but i found that the hold prot of CJ & the knockback pro of acrobatics has saved my butt numerous times. Keep your stuff to single target atacks, you'll find you get enough aggro with FS. Another tip, best place to be in right in the mud pots/blazing aura etc of your pet tanker, cos they ain't going to hit you if they are attacking the aggro magnet.
I have a couple of accuracies in all my attacks & don't seem to have much of a problem, missing rarely. I have 3 accuracies in FS, Siphon Speed & Siphon Power & tend to miss even less. If you need any in tips at any time feel free to gimme a shout
The Good:
Krazy Mary L50 Kinetic defender
Uniqua L31 PeaceBringer
Black Annis L24 Warshade
Krystal L18 Ice Blaster
The Bad:
Frenzi L34 SS/Inv Brute
I get by with 2 Accuracies in Transfusion, Transference, FS, Siphon Speed and Power, and one in all my attacks, and even without tactics I hardly ever seem to miss, untill the enemies go above orange conning, and then the attacks get a bit dicey but even up to purples I find Transfusion and Transference reliable enough. Thats on my lovely Offendery build.
On the points about IR and SJ... My kin was my first toon and I just couldn't face not having him fly, until I got my PB and could fly all I wanted, so I only specced him into IR and acrobatics at 50, but since I've played him more I really, really wish I'd done that earlier. The jumping around is good (unsupressed! yay!) but the acrobatics makes such a difference its amazing - no more getting knowcked out of my own FS! Woooo!
Anyway, hope that ramble helped, just my 2 inf
I agree with Psionetic about the 2 acc in kinetics/1acc in attacks + leadership.
I run all three leadership buffs and have medicine pool for the stun protection of the self heal (and also as a backup plan for if I have bitten off more than I can chew) and for having a rez.
Haven't had repel in a very long time and got fed up of reapplying ID (and I have stimulant anyway that does most of the same stuff, if slightly slower) so that went. I will retake Repel at a future point (currently lev 33 so probably at 35) and will slot it for endurance reduction. The snipe went at the same time as repel and is staying out. I find that the three single target non-interruptible attacks (can't remember names bolt burst and ??) plus torrent are plenty for a full attack chain with all the kinetics stuff going off. Nova is to come at 38, naturally.
i find repel works fine with just the one end reduction, even when i'm right in the middle sending them everywhere. thats with the leadership powers running as well
Repel definitely works fine with one endrec without stamina if you just clip them rather than try to stand on their heads.
---------------------------------------------
Exported from Ver: 1.7.6.0 of the CoH_CoV Character Builder
---------------------------------------------
Name:
Level: 50
Archetype: Defender
Primary: Kinetics
Secondary: Energy Blast
---------------------------------------------
01) --> Transfusion==> Empty(1)
01) --> Power Bolt==> Empty(1)
02) --> Siphon Power==> Empty(2)
04) --> Energy Torrent==> Empty(4)
06) --> Siphon Speed==> Empty(6)
08) --> Increase Density==> Empty(8)
10) --> Power Burst==> Empty(10)
12) --> Speed Boost==> Empty(12)
14) --> Hurdle==> Empty(14)
16) --> Sniper Blast==> Empty(16)
18) --> Inertial Reduction==> Empty(18)
20) --> Health==> Empty(20)
22) --> Stamina==> Empty(22)
24) --> Aim==> Empty(24)
26) --> Transference==> Empty(26)
28) --> Hasten==> Empty(28)
30) --> Assault==> Empty(30)
32) --> Fulcrum Shift==> Empty(32)
35) --> Explosive Blast==> Empty(35)
38) --> Nova==> Empty(38)
41) --> Thunder Strike==> Empty(41)
44) --> Charged Armor==> Empty(44)
47) --> Power Sink==> Empty(47)
49) --> Repel==> Empty(49)
---------------------------------------------
01) --> Sprint==> Empty(1)
01) --> Brawl==> Empty(1)
01) --> Vigilance==> Empty(1)
02) --> Rest==> Empty(2)
---------------------------------------------
Any kins wanna let me know how to spread the slots out?