The Gladiator's Armor +3% Defense IO allows some wiggle room on your positional defense IO sets. So, which sets do you really dislike, but you took them for their defense bonuses?
Sovereign Right is the one I would probably ditch first. All those status resist bonuses are junk for a Crab Spider, and your Melee defense is still soft-capped without it.
Give the Spiderlings four slots of Expedient Reinforcement, which can include the 10% Resist unique if you want it. Slot #5 can be the Sovereign Right resist bonus unique. Slot #6 could be added to Health and slotted with the Panacea proc.
Call Reinforcements could also be tweaked a bit. Since you don't really require the ranged defense bonus that Slot #6 gives you, you could get rid of your least favorite IO from that set and replace it with a Recharge IO, giving you more quality time with your pets.
Minor point: I assume that Aegis Resist/Recharge in Fortification is meant to be a Resist/Endurance?
I do wonder something, on provoke I understand you use it for tanking/pet control. But why not 2 slot it and add a acc value to it. I assume you know that the presence power pool powers are unlike scrapper challange and tank taunts are not auto hit? Adding in two mocking beratement would add 1.8 more end to your build and bring up your recovery slightly along with decreasing your miss factor even with a fully slotted tactics. It would also help offset a tiny bit of the 1.8/1.3 with incarnate on end drain. Also if you wanted to and had slots leftover from optimizing, getting beratement to 5 slots would add more aoe and melee defence.
The only other thing I can comment on is why not switch places on SJ and combat jump so that you have a real travel power earlier? I get that this is a build used to tank things at lvl 50, and that with ninja run and beast run you dont really need a travel power as early as you used too in this game. But if you exempt at all, which I can see your not planning to anytime soon, wouldnt a true travel be better?
Now we aren't ready quite yet to let the catgirls out of the bag.... (quote from ex libris)
I tank things at any level. :P
So made some changes, perma hasten, etc. Any feedback?
Hero Plan by Mids' Hero Designer 1.954
http://www.cohplanner.com/
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Anansi Spider: Level 50 Natural Arachnos Soldier
Primary Power Set: Crab Spider Soldier
Secondary Power Set: Crab Spider Training
Power Pool: Fighting
Power Pool: Leaping
Power Pool: Speed
Power Pool: Presence
Hero Profile:
Level 1: Channelgun -- Apoc-Dmg:50(A), Apoc-Dmg/Rchg:50(3), Apoc-Acc/Dmg/Rchg:50(3), Apoc-Acc/Rchg:50(5), Apoc-Dam%:50(5), Achilles-ResDeb%:20(7)
Level 1: Crab Spider Armor Upgrade -- GA-3defTpProc:30(A), S'fstPrt-ResDam/Def+:30(7)
Level 2: Combat Training: Defensive -- LkGmblr-Rchg+:50(A)
Level 4: Longfang -- ShldBrk-DefDeb:30(A), ShldBrk-Acc/DefDeb:30(11), ShldBrk-Acc/Rchg:30(11), ShldBrk-DefDeb/EndRdx/Rchg:30(13), ShldBrk-Acc/EndRdx/Rchg:30(13), ShldBrk-%Dam:20(15)
Level 6: Boxing -- Dmg-I:50(A)
Level 8: Suppression -- SDoArach-Acc/Dmg:50(A), SDoArach-Dmg/Rchg:50(15), SDoArach-Acc/Dmg/Rchg:50(17), SDoArach-Dmg/EndRdx/Rchg:50(17), SDoArach-Rchg/DmgFear%:50(19)
Level 10: Tactical Training: Maneuvers -- LkGmblr-Rchg+:50(A), LkGmblr-Def:50(19), LkGmblr-Def/EndRdx:50(21)
Level 12: Combat Jumping -- LkGmblr-Rchg+:50(A), LkGmblr-Def:50(21), Zephyr-Travel:50(23), Zephyr-Travel/EndRdx:50(23), Zephyr-ResKB:50(25)
Level 14: Tough -- Aegis-ResDam:50(A), Aegis-ResDam/EndRdx:50(25), S'fstPrt-ResKB:30(27)
Level 16: Hasten -- RechRdx-I:50(A), RechRdx-I:50(27)
Level 18: Arm Lash -- Oblit-Dmg:50(A), Oblit-Acc/Rchg:50(29), Oblit-Dmg/Rchg:50(29), Oblit-Acc/Dmg/Rchg:50(31), Oblit-Acc/Dmg/EndRdx/Rchg:50(31), Oblit-%Dam:50(31)
Level 20: Weave -- LkGmblr-Rchg+:50(A), LkGmblr-Def:50(33), LkGmblr-Def/EndRdx:50(33)
Level 22: Mental Training -- Run-I:50(A)
Level 24: Fortification -- Aegis-ResDam:50(A), Aegis-ResDam/EndRdx:50(33), Aegis-ResDam/Rchg:50(46)
Level 26: Frenzy -- Oblit-Dmg:50(A), Oblit-Acc/Rchg:50(34), Oblit-Dmg/Rchg:50(34), Oblit-Acc/Dmg/Rchg:50(34), Oblit-Acc/Dmg/EndRdx/Rchg:50(36), Oblit-%Dam:50(36)
Level 28: Provoke -- Taunt-I:50(A)
Level 30: Tactical Training: Leadership -- GSFC-ToHit:50(A), GSFC-ToHit/Rchg:50(36), GSFC-ToHit/Rchg/EndRdx:50(37), GSFC-Rchg/EndRdx:50(37), GSFC-ToHit/EndRdx:50(37), GSFC-Build%:50(39)
Level 32: Tactical Training: Assault -- EndRdx-I:50(A)
Level 35: Venom Grenade -- Posi-Acc/Dmg:50(A), Posi-Dmg/EndRdx:50(39), Posi-Acc/Dmg/EndRdx:50(39), Posi-Dmg/Rchg:50(40), Posi-Dmg/Rng:50(40)
Level 38: Omega Maneuver -- Amaze-Stun:50(A), Amaze-Stun/Rchg:50(40), Amaze-Acc/Stun/Rchg:50(42), Amaze-Acc/Rchg:50(42), Amaze-ToHitDeb%:50(42)
Level 41: Call Reinforcements -- C'Arms-Acc/Rchg:30(A), C'Arms-Acc/Dmg:30(43), C'Arms-Dmg/EndRdx:30(43), C'Arms-Acc/Dmg/Rchg:30(43), C'Arms-EndRdx/Dmg/Rchg:30(45), C'Arms-+Def(Pets):30(45)
Level 44: Summon Spiderlings -- ExRmnt-Acc/Dmg/Rchg:30(A), ExRmnt-Acc/Rchg:50(45), ExRmnt-EndRdx/Dmg/Rchg:50(46), ExRmnt-Acc/Dmg:50(46)
Level 47: Serum -- Dct'dW-Heal/EndRdx:50(A), Dct'dW-Heal/Rchg:50(48), Dct'dW-Heal:50(48), Dct'dW-Rchg:50(48), Dct'dW-EndRdx/Rchg:50(50)
Level 49: Super Jump -- Zephyr-ResKB:50(A), Zephyr-Travel:50(50), Zephyr-Travel/EndRdx:50(50)
Level 50: Void Radial Judgement
Level 50: Diamagnetic Core Flawless Interface
Level 50: Cardiac Core Paragon
Level 0: Freedom Phalanx Reserve
Level 0: Portal Jockey
Level 0: Task Force Commander
Level 0: The Atlas Medallion
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Level 1: Brawl -- Dmg-I:50(A)
Level 1: Conditioning
Level 1: Sprint -- Clrty-Stlth:50(A)
Level 2: Rest -- RechRdx-I:50(A)
Level 4: Ninja Run
Level 2: Swift -- Run-I:50(A)
Level 2: Health -- Numna-Regen/Rcvry+:50(A), Mrcl-Rcvry+:40(9)
Level 2: Hurdle -- Jump-I:50(A)
Level 2: Stamina -- P'Shift-End%:50(A), P'Shift-EndMod:50(9)
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Code:
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So nothing else people can suggest to refine my build? I'm wanting to get this done before I start work on my next project.
Maybe it's just me, but I pulled your build up in Mids. You seem to suffer on endurance quite a bit. I do like how you're over the soft cap for the 3 main positions though. I was just wondering if smash and lethal were worth getting up there too or not? Otherwise, really nice build. 
Virtue H&V: CatSquid of Justice-Lvl 37 TriForm PB, Tundra Tigress-Lvl 50 Claws/SR Scrapper, Mistress Khaos-Lvl 50 Dark/Fire Brute, D'Vine Death-Lvl 50 Plant/Thorn Dom, Phrozen Purrgatory-Lvl 50 Ice/Cold Corr, Prowling Pantheress-Lvl 50 Claws/Nin Stalker, Robo Mynx 3.0-Lvl 50 Bots/Traps MM, ArachniBlast-Lvl 50+3 Perma Hasten/Perma Pets/High Recharge Crabspider, Devil's Wrath-Lvl 50 Bane Spider. SG: The 912 Project, VG: Progressively Evil.
So I'm now rich enough to start refining and finalising my build. With the PvP price crash etc, I'm able to afford pretty much anything.
So here is what is looking to be my finalised build.
Feedback is appreciated.