Depends on the power, and how Domination is coded to affect it.
One power that comes to my mind would be Arctic Air, which is autohit and benefits from Domination, giving another chance to give a longer confuse on top of the normal chance.
Then there's Impale, with its immobilize effect, which currently does not benefit from Domination. And it has a ToHit check 
Oooo I didnt know that AA was affected by Domination. So is Drain Psyche and powersink affected by Domination or not?
Just so i get it right.
Any power that does not need an accuracy check is not enhanced by domination ?