/Regen is probably best solo, as it is "Flat" rather than "Proportional" damage mitigation.
Having said that, the parry of ninja blade combined with /SR is a very attractive combination giving you sky high defence.
Both would be very solo-able IMO. /Regen would probably better at low levels (complicated maths regarding damage mitigation...boring) and slightly better even at higher levels.
If you just want to PvE, I wouldnt bother with aid self myself... just keep that defence rocketing up and rest occassionally.
The bonous you get from manuevers would be fractional... its not worth it even in a big team. Weave is more helpful but I would keep it rather low priority myself.
Id go with concept personallly. And fun. I prefer the comedy value of never getting hit - aswell as the sense of danger it gives you - a couple of flukes and you are suddenly sweating 
Hmm well im going to lvl them both up and once I9 hits ill respec them both on test to see which is better. I think they can both be very well in later lvls
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Weave is more helpful but I would keep it rather low priority myself.
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Please use my simple technique for revising the following.
Read, cover, and repeat.
WEAVE IS A POINTLESS POWER.
Personally, I'm a massive fan of /SR for Stalkers, for me it wins hands down over /Regen.
/SR gives you +Peception from Focused Senses which /Regen cant offer, which comes in handy for dealing with the likes of Smoke Grenades or should you choose to venture into PvP
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If you do go /SR then Aid Self is not to be ignored, I've found it has saved me from faceplanting on several occassions on my Claws/SR Stalker who has his Defences maxed out.
Thing to remember with /Regen is that you are regenerating HP on a Melee AT with a low base HP, I find it somewhat trickier that a /Regen Scrapper to play.
Oh and MoG vs Elude, I think Elude wins that round boys and girls.
I know it's not one of the sets you were initially considering, but would */ninjitsu not be a viable option?
It's a Def based set like /SR, but comes ready with it's own self heal, thus freeing up a power choice for another power of your choice.
Just a thought, I'm not a big numbers kinda guy, so can't quote the actual defense figures of Ninjitsu in comparison to Super Reflexes, but it's always my prefered choice for stalkers
I already got a Nin stalker, Prodigal Son, EM / NIN - He's just sat at 24 waiting for me to lvl him lol, havnt touched him in ages.
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Weave is more helpful but I would keep it rather low priority myself.
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Please use my simple technique for revising the following.
Read, cover, and repeat.
WEAVE IS A POINTLESS POWER.
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Its not pointless if stacked with other defence powers. Im not saying its great, mind.
Lets say you allready have 25% defence = 50% damage mitigation.
If you only get another 2.5% defence from weave (say... figures may vary)
This does not mean that you will get 5% less damage than you where used to...
It actually means you get 10% less damage than you where used too... (enemies used to hit 25% of the time, now they hit 22.5% of the time)....
Oh, it also means you will get mezzed, debuffed, slowed, immobilised, and end drained 10% less than you are used too.
Whilst Im not saying Weave is great, it has its place as stacking defence is a tasty thing.
Regen isn't a great choice for a stalker. Heals are all based on regenerating a percentage of your hit points each tick. Scrappers have buckets of hit points, so regen Scrappers are great. Stalkers have the lowest hit points in the game, so regen has a considerably reduced effect.
Disclaimer: The above may be humerous, or at least may be an attempt at humour. Try reading it that way.
Posts are OOC unless noted to be IC, or in an IC thread.
Regen are great for stalkers, both for pve and for pvp. True the quick HP recovery is not that great due to the little hit points they have, but having dull pain and reconstruction, besides IH, your survavility is greatly boosted. I found my em regen much easier to play than my spines sr for instance, that's why my em regen is lv50 and the spiney still 43
Yeah, but SR lacks self heals. I haven't tried them all, but my 'imformed guess' would be that Ninjutsu probably outshines both of them.
Disclaimer: The above may be humerous, or at least may be an attempt at humour. Try reading it that way.
Posts are OOC unless noted to be IC, or in an IC thread.
Ok so i have roled another stalker, another Alt for that matetr.
I am in a bit of a situation, i dont know wheather to pick Regen or SR. My primary is Ninja Blade as i havnt really used it much and i think it could be good
Anyway back to the decsision, Regen or SR, i will be using him for solo'ing / killing highest i can :P AV's, heroes and that :P. I wont be using him for pvp but if i get bored one night i wouldnt mind going in RV or Sirens.
So i like regen as it seems to have everything....Lots of nice heals and +regen, it has defense (only lil but hey) a god mode and a revive. Should i get aidself in this build for that extra heal ( doesnt seem like a good idea tho)
I like SR as it has very high defense, has quickness had a cool god mode. However it lacks a heal so i will be taking aidself!! Is it worth gettin Manuvers and Weave (if i can fit it in) is it worth it for both sets?? (dont see the point in running tough, uses end and takes up slots and its resist not defense)
Could anyone give me some advice on these and some feedback to what i have said, im really not sure as i havnt played these before and just want to be pointed in the right direction.