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Yeah, I think the special is unresistable in PvP but not in PvE which confused me a little. Only noticed when my AS was doing very poor damage against CoT spectral knights, etc as they are smashing resistant.
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Spectral knights also have a similar resistnace to lethal. I can't one shot CoT spectral minions at level 26.
@Unthing ... Mostly on Union.
@Zephyrus: A little more clarification would be helpfull... suppose you need build-up for those nevertheless. And to which Zone do you refer?
Yes i use build up, i've now changed to 1 Acc SO 5 Damage and have 2 ToHit buffs in build up, this helps to make sure its a 1 hit death as sometimes they were left with a tiny bit of hp after AS. Not sure if it will make much difference but at some point i'll probably try 6 slotting it for damage and put more tohit buffs in build up, especially if we get focused accuracy in epics.
The zone i'm in is Sirens Call, and usally against lvl 50's.
this is very very very true as long as you use build up and assassins strike while you're invisble and you should kill in one ive done it tons of times and im only A lvl 12 stalkers rock (this will work as long as there not to much off a higher lvl ive done up to 3 lvls ahead of me nicely (p.s use acuracy inhancements and insperations0
Hmm seems part of my post is inaccurate, blasters dont seem to one shot anymore, they are left with the tiniest bit of hp that one more attack finishes off now.
I couldnt one-hit anyone last night. Didnt even take 50% of their HP, and that was using Buld Up + Assassin's Strike (Fought blasters and scrappers mainly). Admittedly I dont even have any DO's on any of my powers yet (2 TO Acc, 3 TO Dmg). My main problem in PvP (espacially one-on-one) is running out of endurance. I was taking very little damage from anyone I was fighting yesterday and was inflicting alot, but lack of endurance forced me to disengage every time (Still no hero kills under my belt 
). Either I had to run fromn lack of endurance or the hero screamed "OmG a st4lker!! Runxxorz!!" and fled flailing their hands like a paragon city cop after one assassin's strike (and, twice, before the assassin's strike because I'd left Stealth off 
)
Most of the heroes were exemped lvl 50's though...
Just to point out to those that think Stalkers can't one shot, i have 2 Acc SO's and 4 Damage SO's on mine and it one shots blasters, controllers and defenders.