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In a comment on an LJ post in the City of Heroes forum, someone complained that the Lysosome Exposure Enhancement was useless and unwanted, because nobody except a Dark/Dark Def could really use it. Inspired, I went to the powers FAQ at Warcry and ran down the list to see which powers could benefit. I've probably missed a few, but here's my survey of people who can use a Lysosome, which is apparently widely regarded as one of the "most useless" Hami-Os in the game.
These are all the powers I could find that can benefit from two out of the three factors enhanced by a Lysosome Exposure (To-Hit Debuff/Defense Debuff/Accuracy):
<ul type="square">[*]Assault Rifle Blasters (Burst)[*]/Device Blasters (Smoke Grenade)[*]Earth Controllers (Stone Prison, Stone Cages)[*]Dark Miasma Defenders (Twilight Grasp, Fearsome Stare, Petrifying Gaze, Dark Servant)[*]/Dark Blast Defenders (most Blast attacks debuff Accuracy)[*]Radiation Emission Defenders (Radiation Infection—though, granted, the Debuff/End Reduc Hami-O is a better choice for this)[*]/Radiation Blast Defenders (most Blast attacks debuff Defense)[*]Storm Summoning Defenders (possibly; I'm not sure if Tornado takes Acc or not)[*]Broadsword Scrappers (Hack, Slash, Whirling Sword, Disembowel, Head Splitter)[*]Claws Scrappers (Slash)[*]Dark Melee Scrappers (most attacks debuff Accuracy)[*]Katana Scrappers (the same attacks as Broadsword, by whatever names they're called now; the guide I'm looking at isn't updated with the new names)[/list]
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nice post and great thread! I just wanted to add that lysos are good for storm defenders or controllers, in freezing rain (which now takes accuracy enhancements too)
regards,
Liam