AgentSnow

Well, for really enjoyable RP background you need to concern yourself with more than just his power origin. The actual catalyst of physical change for the character is only the smallest part of his journey. Who was he before the event and who is he after the event are the really important things. Why does he do what he does(fight crime) and what has he left behind to do so(family, hopes, dreams)?

Why did <insert hero group volunteer experiment, villain kidnaper> choose him? How did he <perform in training, escape>? How do <other heroes, villains, civilians> view him? What else does he do during his <spare, off, constant battle> time?

Science origin doesn't necessarly have to mean he was experimented on. He could have been the scientist too. Maybe he dropped the wrong vial.

Dude is married to his job... make her a Villain.

You could try Gynoid, that is like an android only the female equivalent. Guri is a somewhat obscure Star Wars character that was a droid that looked human. You could try to go with Maria, the first gynoid on film was given that name in Metropolis. I'm sure there are a whole horde of female robots in anime you could exploit for names. You could try for AcidBurn, Angelina Jolie's role in Hackers. T-X from Terminator 3 would probably be a bit too obvious of a steal. I suggest looking up a word that means robot and looking at how it is pronounced in other languages. Coltello is italian for knife, so I named my KoA toon Leia Coltello. Gheebyel is Russian for doom, so I have a toon named Dr. Gheebyel.

Medicine pool has worked great for me in the past. A friend and I made identical Fire/Fire blasters that made good use of stimulant on a regular basis in our duo missions. With our damage output we only needed the mez protection for a few seconds, but for those few seconds we REALLY needed it.