Theory of a Night Widow

So finally coming back around to fixing my night widow, I'm playing with some different ideas. Without trying to post any builds, is it viable to build a night widow without dipping into powers outside of the widow pools? I have been getting into the incarnate content and now working on getting destiny opened to start on hybrid. I like being rather offensive-minded and will be prone to wanting too many attacks. Can I still take only the widow defensive powers and still build up enough def and resist without taking weave and tough, or at least not burn through slots on them? Work is getting in the would playing with Mids enough to figure it out and thought I would ask the community.

I've seen many builds but not feeling a consensus on if dart burst or poison dart is the better ranged attack. I feel psychic scream can be skipped but what about mental blast as a second ranged attack?

Not really looking for builds as much as thoughts on if this is a doable route or if it really does need support via fighting and leadership pools, or just from inherent fitness.

Appreciate it, fellow soldiers of Arachnos!

Good deal! I already have Rebirth constructed and am just waiting to get the last third of the experience needed for it. Is Musculature a good pick for an alpha then? I also have both Reactive and Degenerative for Interface and Ion for Judgement.