I always tell people the more information we have the greater the chance we can piece together a common reason for the crashes (assuming its software related which it often is)
H: Blaster 50, Defender 50, Tank 50, Scrapper 50, Controller 50, PB 50, WS 50
V: Brute 50, Corruptor 50, MM 50, Dominator 50, Stalker 50, AW 50, AS 50
Top 4: Controller, Brute, Scrapper, Corruptor
Bottom 4: (Peacebringer) way below everything else, Mastermind, Dominator, Blaster
CoH in WQHD
Run this program CoHHelper it should give us the important details.
Don't count your weasels before they pop dink!
CoH Helper data:
---System information gathered by CoH Helper version 0.2.0.2---
DxDiag gathered at December 10, 2011 12:46 (-06:00)
Operating System: Windows 7 Home Premium 64-bit (6.1, Build 7601) Service Pack 1 (7601.win7sp1_gdr.110622-1506)
System Manufacturer: System manufacturer
System Model: System Product Name
BIOS: BIOS Date: 01/05/10 22:25:04 Ver: 05.03
Central Processor: AMD Athlon(tm) II X4 630 Processor (4 CPUs), ~2.8GHz
Memory: 4096MB
.Net Memory Report: 2590MB out of 4095MB available
Page File: 6369MB (1818MB currently in use)
C Drive: (WDC WD5000AAKS-00V1A0 ATA Device) 133705MB out of 476837MB (28%) free
D Drive: (HL-DT-ST DVDRAM GH24NS50 ATA Device) zero-size drive
Windows directory location: C:\Windows
DirectX: DirectX 11
DirectX Diag version: 6.01.7601.17514 (64-bit version)
Display Notes: No problems found.
Sound Notes: No problems found.
No problems found.
Input Notes: No problems found.
Monitor:
Monitor's Max Resolution: (blank)
Video Device Name: AMD Radeon HD 6800 Series
Manufacturer / Chip: Advanced Micro Devices, Inc. / ATI display adapter (0x6738)
Video Memory: 2803 MB
Driver Version: 8.902.0.0
Driver Date: 10/12/2011 2:13:00 PM
Driver Language: English
Sound Device Description: Speakers (VIA High Definition Audio)
Driver File: viahduaa.sys
Driver Version: 6.00.0001.7600
Driver Date: 10/20/2009 9:30:32 PM
Sound Device Description: Digital Output Device (HDMI TX0) (VIA High Definition Audio)
Driver File: viahduaa.sys
Driver Version: 6.00.0001.7600
Driver Date: 10/20/2009 9:30:32 PM
WMI Information
Motherboard Manufacturer: ASUSTeK Computer INC.
Motherboard Model: (empty)
Motherboard Product: M4A78LT-M-LE
Motherboard Version: Rev X.0x
BIOS Manufacturer: American Megatrends Inc.
BIOS Name: BIOS Date: 01/05/10 22:25:04 Ver: 05.03
BIOS Version: 010510 - 20100105
BIOS Release: 20100105000000.000000+000
Registry Information for Current User
Resolution: 1360x768
3D Resolution: 1360x768 (Not using renderscale)
Full Screen: Yes
Maximized: No
Screen Position: 0, 0
Refresh Rate: 60Hz
Vertical Sync Enabled: Yes
Physics Quality: High
Maximum Particles: 50000
Max Particle Fill? 10.000
Physics Card Enabled: No
Anti-aliasing: Off
Anisotropic Filtering: 4x
Texture LOD Bias: Smooth
Water Effects: Ultra quality
Bloom: 1.000 (turned on)
Depth of Field Enabled: Yes
Desaturation Effects (Sepia) Enabled: Yes
Shader Detail: High
World Texture Level: Very High
Character Texture Level: Very High
World Detail Level (Vis_Scale): 1.000
Entity Detail Level: 1.000
Shadows Enabled: No
Shadow Mode: Unknown (4)
Shadow Map Shader: High quality
Environmental Reflections: High quality
Advanced Occlusion Settings: No
Ambient Occlusion: High quality
Occlusion Strength: Strong
Blur: Trilateral
Ambient Resolution: Quality
Gamma Correction: 1.000
Geometry Buffers (VBOs) Enabled: Yes
Suppression of FX When Camera Close Enabled: No
Close Suppression Range: 3.000
Show Advertisements: Yes
Audio Mode: Performance
3D Audio: No
FX Sound Volume: 1.000
Music Sound Volume: 0.600
Show Advanced Graphics Options: No
Overall Graphics Quality: 1.000
Reverse Mouse Buttons: No
Save Login Username: Yes
Transfer Rate: 1231390 bytes/second
Current Game Version: 2060.201107262317.0
Installation Directory: C:\Program Files (x86)\City of Heroes
Mod files in the Data directory
No modifications found
Freedom
Blueside: Knight'Hawk, lvl 50, Scrapper
Yellowside: Dark'Falcon (Loyalist), lvl 20, Blaster
That Stinging Sensation #482183
I don't really see anything that stands out so it might just be the fact that ATI and the game seem to be having a lot of problems in general lately.
One thing you might try is lowering your Ambient Occlusion and Occlusion Strength. Those could be messing with the complex reflections coming off of a moving reflective surface at a longer draw distance with that relatively lower resolution setting. Note, I said relatively lower. It's not a bad setting but most people are playing with monitors capable of much higher resolutions so that artifacting is not necessarily something that would be noticed by many people.
Don't count your weasels before they pop dink!
Heh...my monitor is also my TV and that's as high as it goes. 
But thanks for the suggestions, I'll try them when I get home. As far as performance, should I look into upping the speed on my card, let it handle AA and AF instead of the game and things of that nature, or just leave it at factory settings?
Freedom
Blueside: Knight'Hawk, lvl 50, Scrapper
Yellowside: Dark'Falcon (Loyalist), lvl 20, Blaster
That Stinging Sensation #482183
I just let the game handle it myself. The problem is that opengl is much more stressful on video cards than directx. With that in mind I've chosen not to push my card through that extra bit of stress.
But if you check your card's temperature in game and it's well within the safety zone then you can give it a try. There is really no sure way of knowing how it will affect performance until you do try.
Don't count your weasels before they pop dink!
I tried your suggestions Mandu and a couple other things. They seemed to have helped a little, though the game still lags a bit when I first enter a zone. It seems like most of the games I play don't like ATI cards or drivers. 
Appreciate the help though.
Freedom
Blueside: Knight'Hawk, lvl 50, Scrapper
Yellowside: Dark'Falcon (Loyalist), lvl 20, Blaster
That Stinging Sensation #482183
I've noticed a few graphics issues lately running CoH (in Ultra Mode using a Radeon 6870). Up until recently I'd been away for a few months, but when I came back I noticed the game seems to lag quite a bit; at least when I first enter, but occasionally it can go on throughout my time in-game. This is new as even back on my old laptop I don't think I've ever had any real issues with lag. Until a couple days ago, the drivers in my video card was from maybe around May-ish of this year. I since upgraded to the 11.10 drivers from AMD due to a map loading issue I encountered in the last SSA. That seemed to solve that issue, though I can't be 100% sure that really was the fix or if just restarting the game fixed it. Even after the driver update, I'm still getting that lag issue. It's especially noticeable in newer zones, or revamped zones (like Atlas).
Another problem I noticed was while running a mission in the sewers on a new character, the water in some areas was blue until I got closer to it. Not sure if that's a problem on my end, or a glitch with the game.
I guess what I'm trying to do here, is 1) see if I was the only one encountering these issues, and what others did to get around them, and 2) find out what I can do to get the most out of my video card (since I know I can adjust clock speed, let the card take care of AA instead of the game, etc) while still getting the most I can out of Ultra Mode.
If y'all need any more information let me know.
EDIT: System Specs
OS: Windows 7 Home Premium 64 bit SP1 (huh, thought it was SP2...)
Processor: AMD Athlon II X4 630 2.80 Ghz
RAM: 4GB
Graphics: AMD Radeon HD 6870 using factory settings (no overclock, etc) 11.10 drivers
Freedom
Blueside: Knight'Hawk, lvl 50, Scrapper
Yellowside: Dark'Falcon (Loyalist), lvl 20, Blaster
That Stinging Sensation #482183