Who Sees the Evil that Lies in Shadows? Not me!
That system should be able to handle almost all of the eye candy turned up. Not familiar with tweakcoh at all, sorry. When was the last time that program was updated?
Did you try some older drivers? Newest isn't always the best, and can introduce issues at times to systems that were good before. Just a thought, have you checked some other forums if people are having issues with the card and those drivers? guru3d.com has lots o' info in their forums GPU/Driver related.
This seemed kinda odd,
Memory: 6144MB
.Net Memory Report: 2927MB out of 6134MB available
Page File: 6655MB (5610MB currently in use
Seems like alot of pagefile being used for a 6gb system?
Looking at your memory usage...are you running a bunch of stuff in the background?
Just as a side note, did you completely uninstall/clean then install latest drivers when you swapped out cards? Can also try just uninstalling/reinstalling the drivers anyway as they may be corrupt.

We'll see....
Good question. Let me try that.
Ok, I have uninstalled my graphics drivers, restarted the machine, reinstalled the drivers, and no help.
I have fiddled with the settings in CoH Helper, turning some things down, but now the game freezes if I even click the Graphics Options tab!
I think I am going to have to delete and reinstall the game. See what happens then.
I've been having problems with the game since Going Rogue came out. I can turn down some settings in Ultra Mode and run just fine. But I want to see everything there is to see!
When GR came out, I had a NVidia 8800GT card. I could turn some things up, but had to turn down others that had previously been up. Particularly Shadows. I have since upgraded to a GTX 470 card. Again some things can be turned on, but I have a strange problem with Shaodws and a few other settings.
Whenever I even so much as try to turn on Shadows, the game freezes. First video freezes, then sound cuts out about ten seconds later. The same happens if I touch the Ambient Occlusion slider, Bloom Effects, or evern try to off the "Advanced Graphics Settings"option. I thought maybe if I could just turn that off and slide the generic graphics slider on up to Ultra, it would help, but no-go on that either.
When GR first came out, I couldn't run the game at all without it freezing within a minute. TweakCoH fixed that problem, but now, even with my new, improved, shiny card, I can't get the game to look as good as it can. It's very frustrating.
TweakCoH lets me adjust my shader quality to high, but when I get in-game my shadows are disabled. I've updated my graphics drivers religously over the past six years. I do wish that TweakCoH could be updated to reflect the new settings within the game, as this would most likely help me track down where the issue is.
Anyways, here is my CoH Helper log. Any help will be appreciated.
---System information gathered by CoH Helper version 0.2.0.2---
DxDiag gathered at February 14, 2011 22:44 (-07:00)
Operating System: Windows 7 Ultimate 64-bit (6.1, Build 7600) (7600.win7_gdr.101026-1503)
System Manufacturer: System manufacturer
System Model: System Product Name
BIOS: BIOS Date: 05/19/09 12:10:39 Ver: 08.00.15
Central Processor: Intel(R) Core(TM) i7 CPU 920 @ 2.67GHz (8 CPUs), ~2.7GHz
Memory: 6144MB
.Net Memory Report: 2927MB out of 6134MB available
Page File: 6655MB (5610MB currently in use)
Windows directory location: C:\Windows
DirectX: DirectX 11
DirectX Diag version: 6.01.7600.16385 (64-bit version)
Display Notes: No problems found.
Sound Notes: No problems found.
No problems found.
No problems found.
Input Notes: No problems found.
Monitor:
Monitor's Max Resolution: (blank)
Video Device Name: NVIDIA GeForce GTX 470
Manufacturer / Chip: NVIDIA / GeForce GTX 470
Video Memory: 4059 MB
Driver Version: 8.17.12.6658
Driver Date: 1/7/2011 8:27:00 PM
Driver Language: English
Sound Device Description: Speakers (Realtek High Definition Audio)
Driver File: RTKVHD64.sys
Driver Version: 6.00.0001.5859
Driver Date: 5/23/2009 2:04:22 AM
Sound Device Description: Realtek Digital Output (Realtek High Definition Audio)
Driver File: RTKVHD64.sys
Driver Version: 6.00.0001.5859
Driver Date: 5/23/2009 2:04:22 AM
Sound Device Description: Digital Output(RCA+Optical) (Realtek High Definition Audio)
Driver File: RTKVHD64.sys
Driver Version: 6.00.0001.5859
Driver Date: 5/23/2009 2:04:22 AM
WMI Information
Motherboard Manufacturer: ASUSTeK Computer INC.
Motherboard Model: (empty)
Motherboard Product: P6T
Motherboard Version: Rev 1.xx
BIOS Manufacturer: American Megatrends Inc.
BIOS Name: BIOS Date: 05/19/09 12:10:39 Ver: 08.00.15
BIOS Version: 051909 - 20090519
BIOS Release: 20090519000000.000000+000
Registry Information for Current User
Resolution: 1920x1178
3D Resolution: 1920x1178 (Not using renderscale)
Full Screen: No
Maximized: Yes
Screen Position: 0, 0
Refresh Rate: 60Hz
Vertical Sync Enabled: Yes
Physics Quality: Low
Maximum Particles: 100
Max Particle Fill? 10.000
Physics Card Enabled: No
Anti-aliasing: 8x
Anisotropic Filtering: 8x
Texture LOD Bias: Crisp
Water Effects: Ultra quality
Bloom: 1.000 (turned on)
Depth of Field Enabled: Yes
Desaturation Effects (Sepia) Enabled: Yes
Shader Detail: High
World Texture Level: Very High
Character Texture Level: Very High
World Detail Level (Vis_Scale): 1.000
Entity Detail Level: 1.000
Shadows Enabled: Yes
Shadow Mode: Disabled
Shadow Map Shader: Unknown (0)
Environmental Reflections: Ultra quality
Advanced Occlusion Settings: No
Ambient Occlusion: High performance
Occlusion Strength: Slight
Blur: Fast
Ambient Resolution: High performance
Gamma Correction: 1.000
Geometry Buffers (VBOs) Enabled: Yes
Suppression of FX When Camera Close Enabled: Yes
Close Suppression Range: 3.000
Show Advertisements: Yes
Audio Mode: Compatiblity
3D Audio: No
FX Sound Volume: 1.000
Music Sound Volume: 0.600
Show Advanced Graphics Options: Yes
Overall Graphics Quality: 0.000
Reverse Mouse Buttons: No
Save Login Username: Yes
Transfer Rate: 1035404 bytes/second
Current Game Version: 1950.201102010039.0
Installation Directory: D:\City of Heroes
Mod files in the Data directory
.\fonts has 1 file
.\texture_library\GUI\Icons\Powers has 146 files
.\texture_library\MAPS\city has 1 file
.\texture_library\MAPS\Midnight_Squad has 1 file
.\texture_library\MAPS\Safeguard has 9 files
.\texture_library\MAPS\sewers has 44 files
.\texture_library\MAPS\static has 41 files
.\texture_library\V_MAPS\Outdoor_Missions has 9 files
.\texture_library\V_MAPS\Static has 16 files