My suggestions would be these:
Defense - especially S/L
HP - between HPT and bonus HP, you can end with a ton
Recharge - to help your offense
I would say any APP/PPP that gives you a TAoE. I like ones with a nice ST ranged attack, too (Fblast/Fball, Gloom/DOblit, MLightning/BLightning, etc.).
HP/Regen
Defense
APP: Energy
So my WP/Fire just hit 50 and I have a few questions...
What should i work towards for IOing? Maybe higher Regen? or Defense?
And any advice on what patron pool to choose? I'm thinking soul for some -tohit to help /fire out and extra damage or energy for Physical Perfection to raise regen/recov and Focused Accuracy