Poison's Noxious Gas

Originally Posted by Poison Pill's Thugs/Traps Guide

Noxious Gas: You can infect one of your Henchmen, surrounding him with a Noxious Gas. All foes near the infected Henchmen will be overcome with the Noxious Gas. Their Defense, Accuracy, Damage and Damage resistance will all be reduced. Additionally, there is a chance than any affected humanoid enemy will become violently ill. Even the mightiest foe will stop dead in their tracks, and left helpless as he empties the contents of his stomach.

Level: 38
Range: 30
End: 22.75
Duration: 45 Seconds
Recharge: 300 seconds

This is it, this is why you take thugs and poison. Noxious Gas works when applied to a pet and creates a 30' gaseous cloud around the pet. It only lasts 45 seconds so the pet needs to be up close and personal with the target and stay there to get the biggest affect. Since the bruiser works best when he's in the middle of the action it creates the best synergy of the two powers. It may take a level or two to really get the hang of it down to maximize the effectiveness so give it a chance. Now let's look at the numbers to see why NG is such a big deal:

-10% ToHit to Target for 20 seconds

-20% Smashing Enhancement to Target for 20 seconds
-20% Lethal Enhancement to Target for 20 seconds
-20% Fire Enhancement to Target for 20 seconds
-20% Cold Enhancement to Target for 20 seconds
-20% Energy Enhancement to Target for 20 seconds
-20% negative_Energy Enhancement to Target for 20 seconds
-20% Toxic Enhancement to Target for 20 seconds
-20% Psionic Enhancement to Target for 20 seconds

-20% Defense to Target for 20 seconds

-30% Resistance(Smashing) to Target for 20 seconds
-30% Resistance(Lethal) to Target for 20 seconds
-30% Resistance(Fire) to Target for 20 seconds
-30% Resistance(Cold) to Target for 20 seconds
-30% Resistance(Energy) to Target for 20 seconds
-30% Resistance(negative_Energy) to Target for 20 seconds
-30% Resistance(Toxic) to Target for 20 seconds
-30% Resistance(Psionic) to Target for 20 seconds

Effect 1000 Held to Target for 4 seconds (0% chance) [Non-resistible]

As you can see NG debuffs across the board and it stacks with Envenom and Weaken. Go look again I'll wait. Now note there is a multiplier depending which tier pet you apply Noxious Gas. The numbers above are based on a tier 2 which has 1.00 multiplier. The tier 1 pets have a 0.75 multiplier. Your tier three bruiser has a 1.25 multiplier. Further reinforcing that Noxious Gas and the bruiser have the best synergy. Using the bruiser your debuffs are 12.5%, 25% & 37.5%.