well if its 5 seconds of disorientate unslotted then 3 slotting with so's will increase this to 10 secs (still not great). Generally nukes seem to get slotte either 3 damage and 3 recharge or 3 damage, 2 recharge and 1 acc.
I miss pre ED days of 6 slotted nukes and no limit on the number of villains they could effect... 
Defiant
Proud Member of the Liberty Legion
Venture - Emp/En Defender
Seph - Kat/SR Scrapper
Blizzard - Ice/Storm Controller
Legionelosis - Rad/Rad Defender
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well if its 5 seconds of disorientate unslotted then 3 slotting with so's will increase this to 10 secs (still not great). Generally nukes seem to get slotte either 3 damage and 3 recharge or 3 damage, 2 recharge and 1 acc.
I miss pre ED days of 6 slotted nukes and no limit on the number of villains they could effect...
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Together with herding having no limits 
eden trial will never be the same again...
@Shift
Shift 50 DM/DA Scrapper ][ TTL 50 Kat/Reg Scrapper ][ Shabriel 50 Peacebringer ][ Ion Shift 46 Rad/Rad Corruptor ][ Thermal Shift 35 Fire/Fire Blaster
"A Scrapper is a lot like a chainsaw. Somewhat hard to handle, incredibly dangerous, and by far the most fun when wielded by the slightly insane."
If you're a stormie you probably have freezing rain, try to use your nuke this way :
Aim => Freezing Rain => Nuke
It might seem low damage but for any def who has access to a -RES power it's not bad ; I'm dropping +2/+3 minions with EF, Aim and PBU, nuke slotted 3dam/3rech as Aim takes care of the accuracy.
If you have Howl aswell, Aim + FR + Howl + Nuke could be enough to kill red minions without power build up.
YMMV, but honestly the nukes are the only thing we have better than high level controllers*, so I like to use it as much as I can. 
*then again, a contained fireball does sick things 
I'd slot with disorients as when the bleep hits the fan you can use it and the enemy can be disorientated long enough for you and the team to take control rather than poo damage and all on you after a mere 5 secs.
He will honor his words; he will definitely carry out his actions. What he promises he will fulfill. He does not care about his bodily self, putting his life and death aside to come forward for another's troubled besiegement. He does not boast about his ability, or shamelessly extol his own virtues. - Sima Qian.
Finally got to level 39 and now have my Sonic Nuke with 4 slots in it.
So far I have 1 x acc in it, but am unsure what to add next.
Either: 3 x dam or 3 x disor. I've noticed that UNSLOTTED this nuke does poor damage on a Defender, so would 3 x dam make much of a difference.
As I'm not a damage dealer I've thought about slotting it for it's secondary component - disorientate (and have the damage done as a bonus). As the dis aspect of it only lasts around 5 seconds UNSLOTTED.
The disorientate aspect of the nuke holds minions and lieutenants, and thus I was thinking of waiting until the Tank/Controller etc has aggro then running in... AIM+THUNDERCLAP+NUKE, so that everything is disorientated.
Any suggestions as to my slotting please?