dominators may have the holds, and damage however they don't have the debuffs and self buffs and also self heal which a controller can have. aka a fire/fire dominator would get pwned by a fire/rad or storm controller. As i said its those debuffs which make them powerful, aswell as epic blasts and containment. which can deal enough damage. to take the dominator out.
Lots of Scrappers will eat your face off. Doubly so If they're Scrapapocaylpse and trebly so if they have whirwind.
But an all Mastermind Hamidon Raid? Now that's an idea. Wait for the villain to hero switch over option then we'll go war of attrition on his enormous gelatinous backside!
Killbots? A trifle. It was simply a matter of outsmarting them. You see, killbots have a preset kill limit. Knowing their weakness I sent wave after wave of my own men at them until they reached their limit and shut down.