No, the default world detail can only go up to 2.0 (200%). As you pointed out, you can use commands to refresh up to 4 (400%) until you zone, but it only has an effect on the landscape.. it wont affect NPCs or players in any way, nor is there a way to do so.
Bah seeing ghosties on the distance when it's freaks is disappointing.
Well, on a side note, the draw distance on Voids and GMs is much farther.. lol
I normally play on vis scale 3 or 4 depending on zone but this seems to have no effect on NPCs as I can see them on the edge of my render distance all faded out and ghost like. Is there a command I can use to boost my NPC rendering distance?