Bugged mission: Reproducible
Interesting. I thought you were going to say after defeating the boss and guards, you only need to click one of the glowies for the mission to complete, not all 5. That's the one I notice everytime. Not that I particularly want them to fix that, I hate searching for glowies.
Crashing is bad though.
Update: I sent a /bug as well as a /petition. A GM responded in time. I reproduced the occurrence and I was disconnected. When I logged back in, the GM had completed my mission for me. I lost the merit reward. This brings my total merit rewards lost due to game bugs to 27.
They made changes to this mission (other than the "hang and crash when click" bug).
Now you have to click a glowy before the boss, Archos appears, and now he does a cutscene. When you defeat Archos, you get your Merits and lose all the temp powers (Pieces of the Wheel) immediately, before even leaving the mission (at least if you are the mission owner).
I have yet to retry this, but the one time it didn't crash for me is when I flew over the platform where I expected Archos to be; then when I couldn't find him I clicked a glowy, triggering the cutscene and didn't get the "Lost connection to server" bug.
It may be a workaround that the mausoleum platform needs to be loaded before triggering the cutscene. (This was non-flashback btw, after consistently crashing when clicking any glowy.)
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"Chew Electric Death, Snarling Cur!"

This mission is still bugged. When doing it through Ouroboros sometimes you can complete with no problem and at other times clicking on a glowie will cause you to disconnect.
I don't know if it helped or if the problem just went away, but I cleared all the bad guys out of the castle and it seemed to start working.
I just did this (and had the same problem). I don't know if this is what fixed it or not, but the time it worked I found a glowie and typed in /sync. Additionally I waited a bit before clicking any of the glowies (I was on my ill/FF so stealthing glowies is really easy). Again, I don't know if that's what fixed it but you might try it the next time to see if it does anything for you.
Where exactly is Archos in the mission? I can't find him
I'm doing the Wheel of Destruction story arc via Ouroboros. The final mission is Defeat Archos and his Coven in outdoor instanced map. I enter the mission from Ouroboros. Objective is to click 5 glowies and defeat boss. Whenever I click any of the glowies--either the portal or one of the chests--as soon as the click bar completes, Lost Connection to Mapserver, disconnect.
When I log back in, I am not standing at the Ouroboros portal. The first time I logged back in, I was standing by Mender Tesseract. The second time I logged back in, I am standing next to Twilights Son. The third time I logged back in, I am standing next to Mender Silos.
I tried dropping first to Talos and entering the mission from the train stop instead, but still the same results. I am disconnected from the mapserver immediately upon clicking any glowie in the mission.
EDIT: Also note that after I disconnected from the mission I entered from the Talos train station, when I logged back in, I was *under the map* out near the Argo highway.