I'd like to introduce the concept of the near miss for the super reflexes set. Basically, you have a chance to roll with the blow or be grazed by an attack and only take a certain percentage of the damage, after all being able to react faster doesn't mean you simply stand there and take it every once in awhile, just to see what pain feels like.
It could be an inherent property of the passives or toggles or however you want to work it...have it with ranged and melee (all but psionic?), and change the AoE/cone defenses to damage resistance to better simulate rolling with the blow or jumping out of the way(because we all know that bomb would have killed me had it not miraculously exploded all around me).
You could even try working it into the number of opponents your fighting. Something like more bad guys = lower defense but more near misses and less damage taken per hit, so yeah, I can take on five guys at once, but it's really hard dodging everything...or not, anyways...
Just an idea I had...food for thought. I like the basic idea, but I'm sure there are flaws in my implementation.