Yes.
And you only have to play through one Patron arc to unlock'em all.
"Champion (the Community Server... or GTFO) is like a small town where everyone knows each other's names, for better or worse." -kojirodensetsu.
"If all you have is a hammer, everything looks like a nail." - Maslow's Hammer
Likewise, you can pick a different set via respec.
So i have created a Dual build Crab/Bane arachnos soldier. I was wondering, can you get separate patron sets because I wanted to use Mace Mastery to reduce any redraw for my bane, and was thinking maybe using Ghost Widow for my crab, but am not sure if I can use 2 separate patron powers for my builds.