Most Fun Powersets
Plant/TA Controller, for spamming outrageous holds, immobs, mezzes, debuffs, and damage.
Dark/Fire Scrapper/Brute for great damage, solid yet interesting defenses, and the Midnight Grasp/Burn combo.
Fire/Kin Corrupter. Insane damage, unlimited endurance, and unrestricted SS and SJ that does more for avoiding damage than most defense toggles. ZOOM! BUFF! BLAM!
Bots/Dark Mastermind. Self-sufficient pets with solid damage and loads of debuffs and other team support. Also, Dark Servant.
Kinetics/Archery Defender with the psychic mastery epic. Buffs and more damage than some Blasters make for a good supporter. Rain of Arrows and Psychic Mastery powers will give you plenty of teaming and solo tactical choices. Mass Hypnosis and your ST attacks, Telekinesis and your AoE attacks, or even just using Telekinesis on a bunch of mobs and holding them there while using Transference to keep your endurance maxed.
WP/SS Tanker. It's the easiest tank you can play, and it's got plenty of damage to sling. It also lacks any weaknesses that would make it too weak to tank a certain AV without a couple of buffs, unlike many other tanker primaries.
Too many alts to list.
A fun combination visually is Grav/Strom Controller. Propel provides endless hilarity beaning enemies with the world's largest (and fastest-moving) yard sale, and Lift is like doing ranged wedgies on everyone. Then the storm powers just look awesome and they work really well too, as long as you're not panicked by knockback.
If we are to die, let us die like men. -- Patrick Cleburne
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The rule is that they must be loved. --Jayne Fynes-Clinton, Death of an Abandoned Dog