Are there a certain group of enemies that each origin has? Or even archtype?

I mean, Mourngrymn is my main character. He is a mutant blaster with energy powers. Now is there a certain story line that you will eventually follow once you reach a certain level that will have a certain group of enemies as your main mission goal? Like most of your missions will revolve around the Skulls, or the Clockwork, or the Cricle of Thorns? Is is specific or just random? Just curious for my background origin story. His origin can be found here for those who haven't read it. I have put a lot of thought and effort into this origin so don't start reading it thinking it is only a paragraph long.

Mourngrymn's origin