Excellent guide. I'm lvl 49 rad/rad and most likely have a very similar build to yours. I don't have irradiate, mainly because it didn't fit my build requirements. If I could get one more power, that would probably be it. But with Epic PPs coming, that ain't gonna happen.
As far as the slotting of EM Pulse that you asked for comment, I personally only have it three slotted with holds. I have perma-AM and perma-Hasten, so its recharge time is pretty short (I don't have numbers but it's back pretty quick). Now, if you use it every fight, or want to use it every fight, you would need recharges, but I only use it for larger groups that might sneak in some hits through RI. I find that alternating AB and EMP between the large groups I come across has them both recharging in good time. I don't put any end reducers because once I pop it, the only things I generally need to run are RI and EF and my attacks, and end. regenerates more than fast enough, or at worst, a catch a breath will set me right.
And there is a definite point in the game where you probably should respec., even if you're doing pretty well with your build. I found that low/mid 30's, as the ATs I generally grouped with (everything but blasters) began to get their defining powers, things like Leadership pool powers were not nearly as helpful. So, I found, that when I respec'ed to a build that was much tougher (like the suggested SS and Stealth combo, amongst others) it actually helped when I grouped. The longer you can survive, the more beneficial you are to a team. And one of the greatest things about a rad/rad is, what helps you in solo play, also helps in group play. Nearly every skill in the set is beneficial to you and a group.