I've found that I can make do without Tough by heavily relying on Healing flames -recharge enemies are a problem and this goes doubly so since no tough means no weave and psychic enemies do -recharge, not having so many 3rd party toggles allows me to slot 1 or 2 reduce endurance on powers and allowing me to fight almost indefinately and I do mean almost I've only seen myself loosing out on endurance when fighting AV's I did also eschew the fire sword based attacks due to char concept this has not penalized me much tho as I took fire mastery and got fireblast and fireball.
Outside of Endurance sapping bosses and AV's due to them regenerating too fast and some can actualy put out more damage then I can handle but only some, my fire/fire tank can take just about anything