How big an aim are you looking for? General all purpose PvE (200-300Mil), Cheap-o PvE (50-150M) or an ultimate goal PvE (1-2billion)?
Depending on which, i'll knock something up for you when I can
Well, I would want a general 200-300m first, then aim to the ultimate 
Okay. The below build is pretty close to Permadom. It's pricey. Very pricey. To reduce the price, simply replace some of the purples with other sets while you work towards them. Travel power is ultimately your choice, but I do highly recommend hasten.
Other powerpicks, up to you. This is just how i'd play a mind dom, even if I do dislike Mind's mass hold.
Comments will be below
Villain Plan by Mids' Villain Designer 1.401
http://www.cohplanner.com/
[u]Click this DataLink to open the build![u]
Level 50 Science Dominator
Primary Power Set: Mind Control
Secondary Power Set: Fiery Assault
Power Pool: Fitness
Power Pool: Speed
Power Pool: Medicine
Ancillary Pool: Soul Mastery
Villain Profile:
Level 1: Mesmerize <ul type="square">[*] (A) Call of the Sandman - Accuracy/Recharge[*] (3) Call of the Sandman - Endurance/Sleep[*] (3) Call of the Sandman - Accuracy/Endurance[*] (5) Call of the Sandman - Sleep/Range[*] (5) Call of the Sandman - Accuracy/Sleep/Recharge[/list]Level 1: Flares <ul type="square">[*] (A) Recharge Reduction IO[/list]Level 2: Dominate <ul type="square">[*] (A) Lockdown - Accuracy/Hold[*] (7) Lockdown - Accuracy/Recharge[*] (7) Lockdown - Recharge/Hold[*] (9) Lockdown - Endurance/Recharge/Hold[*] (9) Lockdown - Accuracy/Endurance/Recharge/Hold[*] (11) Lockdown - Chance for +2 Mag Hold[/list]Level 4: Incinerate <ul type="square">[*] (A) Crushing Impact - Accuracy/Damage[*] (11) Crushing Impact - Damage/Endurance[*] (13) Crushing Impact - Damage/Recharge[*] (13) Crushing Impact - Accuracy/Damage/Recharge[*] (15) Crushing Impact - Damage/Endurance/Recharge[/list]Level 6: Confuse <ul type="square">[*] (A) Coercive Persuasion - Confused[*] (15) Coercive Persuasion - Confused/Recharge[*] (17) Coercive Persuasion - Accuracy/Confused/Recharge[*] (17) Coercive Persuasion - Accuracy/Recharge[*] (19) Coercive Persuasion - Confused/Endurance[*] (31) Coercive Persuasion - Contagious Confusion[/list]Level 8: Swift <ul type="square">[*] (A) Run Speed IO[/list]Level 10: Hasten <ul type="square">[*] (A) Recharge Reduction IO[*] (19) Recharge Reduction IO[*] (21) Recharge Reduction IO[/list]Level 12: Fire Blast <ul type="square">[*] (A) Thunderstrike - Accuracy/Damage[*] (21) Thunderstrike - Damage/Endurance[*] (23) Thunderstrike - Damage/Recharge[*] (23) Thunderstrike - Accuracy/Damage/Recharge[*] (25) Thunderstrike - Accuracy/Damage/Endurance[/list]Level 14: Super Speed <ul type="square">[*] (A) HamiO:Microfilament Exposure[/list]Level 16: Fiery Embrace <ul type="square">[*] (A) Recharge Reduction IO[*] (25) Recharge Reduction IO[*] (46) Recharge Reduction IO[/list]Level 18: Health <ul type="square">[*] (A) Numina's Convalescence - +Regeneration/+Recovery[/list]Level 20: Stamina <ul type="square">[*] (A) Endurance Modification IO[*] (27) Endurance Modification IO[*] (27) Endurance Modification IO[/list]Level 22: Mass Hypnosis <ul type="square">[*] (A) Fortunata Hypnosis - Sleep[*] (29) Fortunata Hypnosis - Sleep/Recharge[*] (29) Fortunata Hypnosis - Accuracy/Sleep/Recharge[*] (31) Fortunata Hypnosis - Accuracy/Recharge[*] (31) Fortunata Hypnosis - Sleep/Endurance[/list]Level 24: Total Domination <ul type="square">[*] (A) Unbreakable Constraint - Hold[*] (33) Unbreakable Constraint - Hold/Recharge[*] (33) Unbreakable Constraint - Accuracy/Hold/Recharge[*] (33) Unbreakable Constraint - Accuracy/Recharge[*] (34) Unbreakable Constraint - Endurance/Hold[/list]Level 26: Terrify <ul type="square">[*] (A) Glimpse of the Abyss - Accuracy/Recharge[*] (34) Glimpse of the Abyss - Endurance/Fear[*] (34) Glimpse of the Abyss - Accuracy/Endurance[*] (36) Glimpse of the Abyss - Fear/Range[*] (36) Glimpse of the Abyss - Accuracy/Fear/Recharge[/list]Level 28: Consume <ul type="square">[*] (A) Performance Shifter - EndMod/Recharge[*] (36) Efficacy Adaptor - EndMod/Recharge[*] (37) Recharge Reduction IO[/list]Level 30: Aid Other <ul type="square">[*] (A) Recharge Reduction IO[/list]Level 32: Mass Confusion <ul type="square">[*] (A) Malaise's Illusions - Accuracy/Recharge[*] (37) Malaise's Illusions - Endurance/Confused[*] (37) Malaise's Illusions - Accuracy/Endurance[*] (39) Malaise's Illusions - Confused/Range[*] (39) Malaise's Illusions - Accuracy/Confused/Recharge[/list]Level 35: Aid Self <ul type="square">[*] (A) Doctored Wounds - Heal/Endurance[*] (39) Doctored Wounds - Endurance/Recharge[*] (43) Doctored Wounds - Heal/Recharge[*] (45) Doctored Wounds - Heal/Endurance/Recharge[*] (50) Doctored Wounds - Heal[/list]Level 38: Blaze <ul type="square">[*] (A) Apocalypse - Damage[*] (40) Apocalypse - Damage/Recharge[*] (40) Apocalypse - Accuracy/Damage/Recharge[*] (40) Apocalypse - Accuracy/Recharge[*] (42) Apocalypse - Damage/Endurance[*] (42) Apocalypse - Chance of Damage(Negative)[/list]Level 41: Dark Embrace <ul type="square">[*] (A) Aegis - Psionic/Status Resistance[*] (42) Aegis - Resistance/Endurance[*] (43) Aegis - Resistance[*] (43) Endurance Reduction IO[/list]Level 44: Soul Drain <ul type="square">[*] (A) Adjusted Targeting - Endurance/Recharge[*] (45) Adjusted Targeting - To Hit Buff/Endurance/Recharge[*] (45) Adjusted Targeting - To Hit Buff/Recharge[*] (46) Adjusted Targeting - To Hit Buff[*] (46) Adjusted Targeting - To Hit Buff/Endurance[/list]Level 47: Combustion <ul type="square">[*] (A) Scirocco's Dervish - Accuracy/Damage[*] (48) Scirocco's Dervish - Damage/Endurance[*] (48) Scirocco's Dervish - Accuracy/Recharge[*] (48) Scirocco's Dervish - Accuracy/Damage/Endurance[/list]Level 49: Telekinesis <ul type="square">[*] (A) Endurance Reduction IO[*] (50) Endurance Reduction IO[*] (50) Endurance Reduction IO[/list]------------
Level 1: Brawl <ul type="square">[*] (A) Empty[/list]Level 1: Sprint <ul type="square">[*] (A) Empty[/list]Level 2: Rest <ul type="square">[*] (A) Empty[/list]Level 1: Domination
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[u]Set Bonus Totals:[u]<ul type="square">[*]15.5% DamageBuff(Smashing)[*]15.5% DamageBuff(Lethal)[*]15.5% DamageBuff(Fire)[*]15.5% DamageBuff(Cold)[*]15.5% DamageBuff(Energy)[*]15.5% DamageBuff(Negative)[*]15.5% DamageBuff(Toxic)[*]15.5% DamageBuff(Psionic)[*]4.38% Defense(Fire)[*]4.38% Defense(Cold)[*]6.88% Defense(Energy)[*]6.88% Defense(Negative)[*]5% Defense(Psionic)[*]10% Defense(Ranged)[*]4.06% Defense(AoE)[*]2.25% Max End[*]2.5% Enhancement(Held)[*]2.75% Enhancement(Terrorized)[*]5% Enhancement(Sleep)[*]6.5% Enhancement(Confused)[*]4% Enhancement(Heal)[*]71% Enhancement(Accuracy)[*]73.8% Enhancement(RechargeTime)[*]4% FlySpeed[*]80.1 HP (7.88%) HitPoints[*]4% JumpHeight[*]4% JumpSpeed[*]MezResist(Held) 2.2%[*]MezResist(Immobilize) 2.2%[*]MezResist(Terrorized) 2.2%[*]16.5% (0.28 End/sec) Recovery[*]26% (1.1 HP/sec) Regeneration[*]6.3% Resistance(Fire)[*]6.3% Resistance(Cold)[*]1.26% Resistance(Energy)[*]4.39% Resistance(Negative)[*]2.55% Resistance(Psionic)[*]9% RunSpeed[/list]------------
[u]Set Bonuses:[u]
[u]Call of the Sandman[u]
(Mesmerize)<ul type="square">[*] 5% Enhancement(Sleep)[*] 19.1 HP (1.88%) HitPoints[*] 2.25% Max End[*] 6.25% Enhancement(RechargeTime)[/list][u]Lockdown[u]
(Dominate)<ul type="square">[*] 3% DamageBuff(All)[*] 2.5% Enhancement(Held)[*] MezResist(Held) 2.2%[*] 2.5% Defense(AoE), 1.25% Defense(Fire), 1.25% Defense(Cold)[*] 3.75% Defense(Ranged), 1.88% Defense(Energy), 1.88% Defense(Negative)[/list][u]Crushing Impact[u]
(Incinerate)<ul type="square">[*] MezResist(Immobilize) 2.2%[*] 11.4 HP (1.13%) HitPoints[*] 7% Enhancement(Accuracy)[*] 5% Enhancement(RechargeTime)[/list][u]Coercive Persuasion[u]
(Confuse)<ul type="square">[*] 4% (0.07 End/sec) Recovery[*] 4% Enhancement(Confused)[*] 4% DamageBuff(All)[*] 10% Enhancement(RechargeTime)[*] 5% Defense(Ranged), 2.5% Defense(Energy), 2.5% Defense(Negative)[/list][u]Thunderstrike[u]
(Fire Blast)<ul type="square">[*] 2% (0.03 End/sec) Recovery[*] 2.5% Defense(Energy,Negative), 1.25% Defense(Ranged)[*] 7% Enhancement(Accuracy)[*] 4% RunSpeed, 4% FlySpeed, 4% JumpSpeed, 4% JumpHeight[/list][u]Fortunata Hypnosis[u]
(Mass Hypnosis)<ul type="square">[*] 4% (0.07 End/sec) Recovery[*] 2.52% Resistance(Fire,Cold)[*] 15% Enhancement(Accuracy)[*] 10% Enhancement(RechargeTime)[/list][u]Unbreakable Constraint[u]
(Total Domination)<ul type="square">[*] 4% (0.07 End/sec) Recovery[*] 2.52% Resistance(Fire,Cold)[*] 15% Enhancement(Accuracy)[*] 10% Enhancement(RechargeTime)[/list][u]Glimpse of the Abyss[u]
(Terrify)<ul type="square">[*] 2.75% Enhancement(Terrorized)[*] 19.1 HP (1.88%) HitPoints[*] 9% Enhancement(Accuracy)[*] 6.25% Enhancement(RechargeTime)[/list][u]Malaise's Illusions[u]
(Mass Confusion)<ul type="square">[*] 2.5% (0.04 End/sec) Recovery[*] 2.5% Enhancement(Confused)[*] 2.5% DamageBuff(All)[*] 6.25% Enhancement(RechargeTime)[/list][u]Doctored Wounds[u]
(Aid Self)<ul type="square">[*] MezResist(Terrorized) 2.2%[*] 1.26% Resistance(Fire,Cold)[*] 4% Enhancement(Heal)[*] 5% Enhancement(RechargeTime)[/list][u]Apocalypse[u]
(Blaze)<ul type="square">[*] 16% (0.68 HP/sec) Regeneration[*] 30.5 HP (3%) HitPoints[*] 4% DamageBuff(All)[*] 10% Enhancement(RechargeTime)[*] 5% Defense(Psionic)[/list][u]Aegis[u]
(Dark Embrace)<ul type="square">[*] 5% RunSpeed[*] 3.13% Defense(Fire,Cold), 1.56% Defense(AoE)[*] 2.55% Resistance(Psionic)[/list][u]Adjusted Targeting[u]
(Soul Drain)<ul type="square">[*] 2% DamageBuff(All)[*] 1.26% Resistance(Energy,Negative)[*] 9% Enhancement(Accuracy)[*] 5% Enhancement(RechargeTime)[/list][u]Scirocco's Dervish[u]
(Combustion)<ul type="square">[*] 10% (0.42 HP/sec) Regeneration[*] 3.13% Resistance(Negative)[*] 9% Enhancement(Accuracy)[/list]
I've geared towards +recharge, in the set bonuses.
The Sleep purple and sleep sets in general are pretty cheap.
Lockdown in dominate, mainly for the proc. Extra mag is always nice.
Confuse purples are worth putting in the ST one over the AoE one, simply because the proc is more noticable and more useful (chance for AoE confuse).
Frankenslotted Consume for maximum recharge and Endurance recovery benefit. With hasten its recharge is 53 seconds.
Medicine pool is always helpful, doctored wounds for the recharge.
GW pool because you don't need the +end from Mu Mastery, and can make the most of Soul Drain's PBAoE Build up effect along with Fiery Embrace to pretty much annihilate an entire spawn on your own.
That's pretty much all I can think of that needs justifying. If you have any questions don't hesitate to PM me 
(I'm expecting, as i've made this build public, to be jumped upon. A few things in the build are personal preferences so please take that into account and edit it to suit YOUR playstyle)
ok, hey thanks for checking here. I have recently got my Dom to 50 and i want to work on two builds a PVP and PVE, i have a decent idea where i'm going with the PVP, but im not sure what to do for PvE, i would really appreciate it if you guys could share a nice PVE build my mind/fire can use
, and all slotted too so i have an aim.
Thanks
Scottie