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In the powers, Aim and Build Up, I want 3 slots of recharge for maximum use but how many should I devote to the ToHit buffs?
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Depends on your secondary and what you want to hit? Aim is +37.5% ToHit, Build Up is +15%, that totals to +52.5%, which is more than enough against pretty much anything (you might still miss against stuff like a MoGed Paragon Protector) if you're not doing PvP.
If you're going for PvP, 1 or 2 slots in Aim might be worth it, depending what you want to go against. Also if you're /Energy and low on slots, get Power Boost, it pretty much doubles the +ToHits.
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Also, what powers are good defence against holds, immobs, sleeps etc? Obviously BF's! but what else?
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Combat Jumping is good against Immobs, Acrobatics is good against Knockback and -down. Aid Self offers some help against Disorient (reducing the time it affects you), Health does the same for sleep. Tactics reduces Confuse and Fear durations against you, Assault does the same for Taunt and Placate.
[b][color=blue]Coldest War /[color=red]/ Omega Patient[/b]
[url="http://www.the-cow.net/"][color=red]The CoW Network (Blog) /[/url][url="http://www.collegeofwar.com/"][color=blue]/ College of War[/url]
Brilliant.
The latest respec on my NRG/NRG blaster looks to have Aim, Build Up and Power Boost and yes he's running shy on slots 
!
Advice on the appropriate slotting, if poss?
"Like War_Hero said, leave it as it is, it toughens up the softies." - Naz Nomad
Union Heroes
War Borg - Leader of The Paragon Knights
Union Villains
McCabe - Co-leader of The Rogue Knights
Defiant - Supreme Hero
Just 3-slot all three with Recharges, you'll be using Power Boost to boost the secondary effects of your stuns anyways, so that's not slots wasted.
Use Power Boost before Aim and Build Up (or you won't get the boost to their tohit) and go wild.
Basically you'll have "problems" only against people who have slotted their Moment of Glory or Personal Force Field with defense enhancements (with 2 accuracies in a standard attack power, you'll be hitting 75% of the time vs. 3-slotted MoG, 95% of the time vs. 2 or worse slotted)
[b][color=blue]Coldest War /[color=red]/ Omega Patient[/b]
[url="http://www.the-cow.net/"][color=red]The CoW Network (Blog) /[/url][url="http://www.collegeofwar.com/"][color=blue]/ College of War[/url]
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[ QUOTE ]
In the powers, Aim and Build Up, I want 3 slots of recharge for maximum use but how many should I devote to the ToHit buffs?
[/ QUOTE ]
Depends on your secondary and what you want to hit? Aim is +37.5% ToHit, Build Up is +15%, that totals to +52.5%, which is more than enough against pretty much anything (you might still miss against stuff like a MoGed Paragon Protector) if you're not doing PvP.
If you're going for PvP, 1 or 2 slots in Aim might be worth it, depending what you want to go against. Also if you're /Energy and low on slots, get Power Boost, it pretty much doubles the +ToHits.
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Just noting , that my PvP blaster has 6-slotted aim and Build up both, 3 recharge, 3 toHit. In addition I have powerboost, 3 recharge. I'm not really interested in calculating how effective or overboard that actually is, as long as I can hit 4 hits out of 5 thru personal forcefield, elude, MoG, radiation infection and Kuji-In retsu like I do I am happy 
(I have to admit that since energy manipulation is pretty easy on slot placement I have slots to spare for this)
ps. as for protection against holds, Im afraid blasters dont get much. Acrobatics is enough to protect you from the autohit hold of telekinesis or 1 blaster-strength hold. THats about it. Force of nature from Force mastery doesnt give mez protection unlike some people seem to think.
Should I worry about the tohits?
"Like War_Hero said, leave it as it is, it toughens up the softies." - Naz Nomad
Union Heroes
War Borg - Leader of The Paragon Knights
Union Villains
McCabe - Co-leader of The Rogue Knights
Defiant - Supreme Hero
ToHits, quite frankly, are needed only in PvP in my opinion.
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ToHits, quite frankly, are needed only in PvP in my opinion.
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/ QFT
Agreeing there. You might want to impress your scrapper friends by bringing down the MoGed PP every once in a blue moon, but that's all you'll gain in PvE from adding ToHit slots.
[b][color=blue]Coldest War /[color=red]/ Omega Patient[/b]
[url="http://www.the-cow.net/"][color=red]The CoW Network (Blog) /[/url][url="http://www.collegeofwar.com/"][color=blue]/ College of War[/url]
In the powers, Aim and Build Up, I want 3 slots of recharge for maximum use but how many should I devote to the ToHit buffs?
Also, what powers are good defence against holds, immobs, sleeps etc? Obviously BF's! but what else?
"Like War_Hero said, leave it as it is, it toughens up the softies." - Naz Nomad
Union Heroes
War Borg - Leader of The Paragon Knights
Union Villains
McCabe - Co-leader of The Rogue Knights
Defiant - Supreme Hero