help~! im in a mish on a team of 8 and we jsut CANT BEAT HIM!
Was in this situation just last night. Mako would get down to 15-20% health and then hit something or other and go right back to nearly full health. After bashing away at him for 20 minutes and going through this pattern several times a couple of us logged and came back with lowbie /Dark and /Rad Corruptors that were promptly lackeyed up. We laid down the debuffs and Mako laid down within 2 minutes.
Easy, but depressing. I'm glad that the regen changes for AVs are being rolled back.
The first several missions are fairly easy to get through, witha defeat all Longbow mish & a rescue Arachnos Operatives mish. The final mission is where it can get really tough.
First of all, you will need to defeat 4 Fonts of Power, all of which have psionic attacks. Having a corruptor with a dark secondary set can help alleviate the psionic damage you will suffer. Then, you will need to defeat Calystix. If you have done the Shaper Cult story arc and/or the Renault SF, you will know that not only is Calystix a strong psionics foe, but he also summons groups of 4-5 Coral Warders as well. Make sure to also touch the multi-colored tooth to activate the ritual, but only after you have defeated the Fonts.
Finally comes the tough part: Mako himself. His minions will attack you first, but they are just cannon fodder. Mako, when his hp get low, will tap the Essence of the Leviathan, which will heal him quickly and make him virtually unhittable by most attacks.
The only way I saw to beat him would be to have 1 or 2 thermal corruptors hit him right away with Melt Armor AND Heat Exhaustion to reduce his defenses and resistances. I also used all 3 Warburg missiles to debuff him further and buff the party. That made it VERY quick to defeat him. He will give the mission owner the Essence of the Leviathan power (+regenerate, -recovery (severe)) for a period of 1 game hour.