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Radiation's buff Accelerate Metabolism protects from all status effects. How is that "zero defense"?
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Wrong!
Accelerate Metabolism does not protect you from status effects, it only shortens their duration. It may be only for a second or two, sometimes not long enough to even notice it, but you can still get stunned/held/slept and have your toggles drop.
Last night three of my SG members and myself, all rad defenders, where combatting DE. With four AMs running I got stunned/mezzed plenty, though it was never for more than a second or two.