SimianOnyx

I think I might have found a good fix for all these problems. On bringing the game up in Safe Mode, and looking at changing the settings to Desktop I saw another option (Windowed) and decided to try it.
I no longer have an invisible mouse in CoX (and no longer have that 'compatiblecursors 1' mouse pointer either), I no longer get the graphical problem (grey scale) when trying to make or tailor a toon.
Just wanted to post this and hopefully get more of you up and running as best as you can.