I like the idea of Defiance but I have a few issues with it.
First it updates far far too slowly. Repeated tests with my blaster have shown between 10 and 12 seconds for it to even start updating. If a blaster is down to less the 40% hp post level 30 they will need the extra damage very quickly in order for it to help out. It's quite easy for two minons for kill me from 30% hp in 5 or 6 seconds.
A second thought is that the hp range for activation needs to be broadened. Raise the starting effect to 75% hp or so and scale the damage buff. I'd suggest adding 10% damage in the 60 to 75% range and 20% between 40 to 60%. Leave the below 40% numbers the same.
Those two changes would make Defiance more useful to all blasters without being overpowering I think.