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L36-40: 1 Hero = 20 minions
L41-45: 1 Hero = 25 minons
L46-50: 1 Hero = 30 minons
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Under this scenario, a team of 8 heroes would be facing 240 minions in a single mission room. I don't need to point out that 1) the rooms aren't big enough for this and 2) most video cards aren't good enough for this. You'd end up with exactly what we have now - small groups hunting massive spawns, while the larger groups are penalized because there's nothing challenging enough for them.
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I think it's a bad idea to dismiss the idea because you're assuming that 8-person groups would be facing even-level minions. There's (in my opinion, at least), a fairly obvious solution to the "facing 240 minions in a single room" problem. Would it not be reasonable to assume that if 1 player can take on even-level things, 8 players would be capable of handling +4 level things?
While I would agree that the number of things the OP is proposing a player can take on is rather high, the concept itself has merit, in my view.