I'm having this ping problem also, though I am not using netstat or herostats, nor have I ever used said programs.
Bouncing from a steady 50 to a stuttery 300+ in periodic spikes, relatively constant at about once every 40 seconds or so.
Combat or power activation induces a more regular period
of spiking, every 5 seconds or thereabouts, with each power activation assuring a spike.
While the game remains essentially playable, it is a bit jarring as prior to the patch I also hadn't experienced this issue.