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Powers can well be slotted in any fashion desired - each slot gives the same amount of benefit, so go with the ratio that you feel comfortable with.
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Actually, thats not true, and I think it's one of the as-yet unadressed probelms of the game.
For damage powers anyway, it's far more efficient to slot for damage than anything else
If anyone wants a break-down of the numbers, feel free to pm me and I'll gladly provide them, or if I get enough requests I'll post them, but the way it works out, assuming you dont have problems with endurance, it's always better to slot attacks for damage than for end redux or recharge time.
