Thanks for the reply, Khenal.
So far I've been more or less following your advice, just by following common sense I've learned from past MMOs. It's good to know the same general rules apply here.
A couple more questions while I'm thinking of it:
1) How many attack powers is too many? Right now I have brawl, a fast attack and a slow attack, and taunt. blue bar has been an issue since I hit 10 or so, but I'm not comfortable standing around with nothing to do in the middle of huge fights.
2) Is there a general prescription to follow as far as enhancement slot allocation? Do I max out my defensive toggles? How much do I need on my attack powers?